Dental pulp defence and repair mechanisms in dental caries

JC Farges, B Alliot-Licht, E Renard… - Mediators of …, 2015 - Wiley Online Library
Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria
into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in …

Pulp stem cells derived from human permanent and deciduous teeth: Biological characteristics and therapeutic applications

X Shi, J Mao, Y Liu - Stem cells translational medicine, 2020 - academic.oup.com
Human pulp stem cells (PSCs) include dental pulp stem cells (DPSCs) isolated from dental
pulp tissues of human extracted permanent teeth and stem cells from human exfoliated …

Influence of root canal disinfectants on growth factor release from dentin

KM Galler, W Buchalla, KA Hiller, M Federlin, A Eidt… - Journal of …, 2015 - Elsevier
Introduction During dentinogenesis, growth factors become entrapped in the dentin matrix
that can later be released by demineralization. Their effect on pulpal stem cell migration …

Inflammation and regeneration in the dentin-pulp complex: a double-edged sword

PR Cooper, MJ Holder, AJ Smith - Journal of endodontics, 2014 - Elsevier
Dental tissue infection and disease result in acute and chronic activation of the innate
immune response, which is mediated by molecular and cellular signaling. Different cell …

Inflammation–regeneration interplay in the dentine–pulp complex

PR Cooper, Y Takahashi, LW Graham, S Simon… - Journal of dentistry, 2010 - Elsevier
OBJECTIVES: Dental tissue disease and trauma provides an excellent model for the
interaction between tissue defence and regenerative processes and has application to many …

EDTA conditioning of dentine promotes adhesion, migration and differentiation of dental pulp stem cells

KM Galler, M Widbiller, W Buchalla… - International …, 2016 - Wiley Online Library
Aim To evaluate the effect of dentine conditioning on migration, adhesion and differentiation
of dental pulp stem cells. Methodology Dentine discs prepared from extracted human molars …

Dentine as a bioactive extracellular matrix

AJ Smith, BA Scheven, Y Takahashi, JL Ferracane… - Archives of oral …, 2012 - Elsevier
As a mineralised connective tissue, dentine is well adapted to its functional role as a major
structural component of the tooth. Although similar in composition to bone, dentine matrix is …

Exploiting the bioactive properties of the dentin-pulp complex in regenerative endodontics

AJ Smith, HF Duncan, A Diogenes, S Simon… - Journal of …, 2016 - Elsevier
Introduction The development of regenerative endodontic therapies offers exciting
opportunities for future improvements in treatment outcomes. Methods Advances in our …

Release of growth factors into root canal by irrigations in regenerative endodontics

Q Zeng, S Nguyen, H Zhang, HP Chebrolu… - Journal of …, 2016 - Elsevier
Introduction The aim of this study was to investigate the release of growth factors into root
canal space after the irrigation procedure of regenerative endodontic procedure. Methods …

Growth factor release from dentine matrix by pulp‐capping agents promotes pulp tissue repair‐associated events

PL Tomson, PJ Lumley, AJ Smith… - International …, 2017 - Wiley Online Library
Aim To characterize growth factor release from dentine by pulp‐capping agents and to
determine the effects of liberated dentine extracellular matrix (dECM) components on pulp …