Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS
TE Faust, G Gunner, DP Schafer - Nature Reviews Neuroscience, 2021 - nature.com
Almost 60 years have passed since the initial discovery by Hubel and Wiesel that changes
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …
mTOR at the nexus of nutrition, growth, ageing and disease
GY Liu, DM Sabatini - Nature reviews Molecular cell biology, 2020 - nature.com
The mTOR pathway integrates a diverse set of environmental cues, such as growth factor
signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half …
signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half …
Neurodevelopmental disorders: from genetics to functional pathways
I Parenti, LG Rabaneda, H Schoen, G Novarino - Trends in Neurosciences, 2020 - cell.com
Neurodevelopmental disorders (NDDs) are a class of disorders affecting brain development
and function and are characterized by wide genetic and clinical variability. In this review, we …
and function and are characterized by wide genetic and clinical variability. In this review, we …
Consensus paper: cerebellum and social cognition
The traditional view on the cerebellum is that it controls motor behavior. Although recent
work has revealed that the cerebellum supports also nonmotor functions such as cognition …
work has revealed that the cerebellum supports also nonmotor functions such as cognition …
The cerebellum and cognition
JD Schmahmann - Neuroscience letters, 2019 - Elsevier
What the cerebellum does to sensorimotor and vestibular control, it also does to cognition,
emotion, and autonomic function. This hypothesis is based on the theories of dysmetria of …
emotion, and autonomic function. This hypothesis is based on the theories of dysmetria of …
Role of gut microbiome in autism spectrum disorder and its therapeutic regulation
Autism spectrum disorder (ASD) is a neurological disorder that affects normal brain
development. The recent finding of the microbiota–gut–brain axis indicates the bidirectional …
development. The recent finding of the microbiota–gut–brain axis indicates the bidirectional …
Cerebellar modulation of the reward circuitry and social behavior
INTRODUCTION Although the cerebellum has long been considered to be a purely motor
structure, recent studies have revealed that it also has critical nonmotor functions. Cerebellar …
structure, recent studies have revealed that it also has critical nonmotor functions. Cerebellar …
Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
The theory and neuroscience of cerebellar cognition
JD Schmahmann, X Guell, CJ Stoodley… - Annual review of …, 2019 - annualreviews.org
Cerebellar neuroscience has undergone a paradigm shift. The theories of the universal
cerebellar transform and dysmetria of thought and the principles of organization of cerebral …
cerebellar transform and dysmetria of thought and the principles of organization of cerebral …
Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits
Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs);
however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain …
however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain …