Modeling and simulation of neocortical micro-and mesocircuitry. Part II: Physiology and experimentation

JB Isbister, A Ecker, C Pokorny, S Bolaños-Puchet… - bioRxiv, 2023 - biorxiv.org
In recent years, large-scale computational models of the cortex have emerged as a powerful
way to study the multi-scale mechanisms of neural processing. However, due to …

Modeling and simulation of rat non-barrel somatosensory cortex. part i: Modeling anatomy

MW Reimann, S Bolaños-Puchet, JD Courcol… - bioRxiv, 2022 - biorxiv.org
The function of the neocortex is fundamentally determined by its repeating microcircuit motif,
but also by its rich, hierarchical, interregional structure with a highly specific laminar …

Efficiency and reliability in biological neural network architectures

DE Santander, C Pokorny, A Ecker, J Lazovskis… - bioRxiv, 2024 - biorxiv.org
Neurons in a neural circuit exhibit astonishing diversity in terms of the numbers and targets
of their synaptic connections and the statistics of their spiking activity. We hypothesize that …

Heterogeneous and non-random cortical connectivity undergirds efficient, robust and reliable neural codes

D Egas Santander, C Pokorny, J Lazovskis, M Santoro… - 2024 - infoscience.epfl.ch
Simplified models of neural networks have demonstrated the importance of establishing a
reasonable tradeoff between memory capacity and fault-tolerance in cortical coding …