Long non-coding RNAs: novel regulators of cellular physiology and function
JA Oo, RP Brandes, MS Leisegang - Pflügers Archiv-European Journal of …, 2022 - Springer
Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA
transcription. They are now understood to play central roles in diverse cellular processes …
transcription. They are now understood to play central roles in diverse cellular processes …
CMC: Cancer miRNA Census–a list of cancer-related miRNA genes
M Suszynska, M Machowska, E Fraszczyk… - Nucleic Acids …, 2024 - academic.oup.com
A growing body of evidence indicates an important role of miRNAs in cancer; however, there
is no definitive, convenient-to-use list of cancer-related miRNAs or miRNA genes that may …
is no definitive, convenient-to-use list of cancer-related miRNAs or miRNA genes that may …
Long non-coding RNAs: Tools for understanding and targeting cancer pathways
Simple Summary Long non-coding RNA (lncRNA) is a type of RNA molecule that show
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …
Discovery and validation of clinically relevant long non-coding RNAs in colorectal cancer
M Snyder, S Iraola-Guzman, E Saus, T Gabaldon - Cancers, 2022 - mdpi.com
Simple Summary Recent efforts in biomedical research have focused on the identification of
molecular biomarkers to improve the diagnosis, prognosis and eventually treatment of the …
molecular biomarkers to improve the diagnosis, prognosis and eventually treatment of the …
Identification of long non-coding RNAs and RNA binding proteins in breast cancer subtypes
Breast cancer is a heterogeneous disease classified into four main subtypes with different
clinical outcomes, such as patient survival, prognosis, and relapse. Current genetic tests for …
clinical outcomes, such as patient survival, prognosis, and relapse. Current genetic tests for …
Molecular mechanisms of lncRNAs in the dependent regulation of cancer and their potential therapeutic use
C García-Padilla, Á Dueñas, V García-López… - International Journal of …, 2022 - mdpi.com
Deep whole genome and transcriptome sequencing have highlighted the importance of an
emerging class of non-coding RNA longer than 200 nucleotides (ie, long non-coding RNAs …
emerging class of non-coding RNA longer than 200 nucleotides (ie, long non-coding RNAs …
Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis
Abstract HOTAIR is a 2.2-kb long noncoding RNA (lncRNA) whose dysregulation has been
linked to oncogenesis, defects in pattern formation during early development, and …
linked to oncogenesis, defects in pattern formation during early development, and …
Urinary extracellular vesicles contain mature transcriptome enriched in circular and long noncoding RNAs with functional significance in prostate cancer
A Almeida, M Gabriel, V Firlej… - Journal of …, 2022 - Wiley Online Library
Long noncoding (lnc) RNAs modulate gene expression alongside presenting unexpected
source of neoantigens. Despite their immense interest, their ability to be transferred and …
source of neoantigens. Despite their immense interest, their ability to be transferred and …
Systematic analysis of DNA methylation-mediated TF dysregulation on lncRNAs reveals critical roles in tumor immunity
J Yin, N Ding, J Yu, Z Wang, L Fu, Y Li, X Li… - … Therapy-Nucleic Acids, 2023 - cell.com
Emerging evidence suggests that DNA methylation affects transcriptional regulation and
expression perturbations of long non-coding RNAs (lncRNAs) in cancer. However, a …
expression perturbations of long non-coding RNAs (lncRNAs) in cancer. However, a …