The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA
transcription. They are now understood to play central roles in diverse cellular processes …

A growing body of evidence indicates an important role of miRNAs in cancer; however, there
is no definitive, convenient-to-use list of cancer-related miRNAs or miRNA genes that may …

Simple Summary Long non-coding RNA (lncRNA) is a type of RNA molecule that show
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …

Simple Summary Recent efforts in biomedical research have focused on the identification of
molecular biomarkers to improve the diagnosis, prognosis and eventually treatment of the …

Breast cancer is a heterogeneous disease classified into four main subtypes with different
clinical outcomes, such as patient survival, prognosis, and relapse. Current genetic tests for …

Deep whole genome and transcriptome sequencing have highlighted the importance of an
emerging class of non-coding RNA longer than 200 nucleotides (ie, long non-coding RNAs …

Abstract HOTAIR is a 2.2-kb long noncoding RNA (lncRNA) whose dysregulation has been
linked to oncogenesis, defects in pattern formation during early development, and …

Long noncoding (lnc) RNAs modulate gene expression alongside presenting unexpected
source of neoantigens. Despite their immense interest, their ability to be transferred and …

Emerging evidence suggests that DNA methylation affects transcriptional regulation and
expression perturbations of long non-coding RNAs (lncRNAs) in cancer. However, a …