Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease

SM de la Monte - Current Alzheimer Research, 2012 - ingentaconnect.com
Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease

SM de la Monte - Drugs, 2012 - Springer
Alzheimer's disease (AD) is the most common cause of dementia in North America. Growing
evidence supports the concept that AD is fundamentally a metabolic disease that results in …

[HTML][HTML] DSM-5 criteria and depression severity: implications for clinical practice

JC Tolentino, SL Schmidt - Frontiers in psychiatry, 2018 - frontiersin.org
Background: Depression diagnosis requires five or more symptoms (Diagnostic and
Statistical Manual of Mental Disorders-DSM-5). One of them must be either Depressed mood …

Diagnostic performance of myocardial innervation imaging using MIBG scintigraphy in differential diagnosis between dementia with Lewy bodies and other dementias …

G Treglia, E Cason - Journal of Neuroimaging, 2012 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE This study was designed to review the
diagnostic performance of myocardial innervation imaging using iodine‐123 …

[HTML][HTML] Functional roles of short sequence motifs in the endocytosis of membrane receptors

KN Pandey - Frontiers in bioscience (Landmark edition), 2009 - ncbi.nlm.nih.gov
Internalization and trafficking of cell-surface membrane receptors and proteins into
subcellular compartments is mediated by specific short-sequence signal motifs, which are …

[HTML][HTML] Decrease in attentional performance after repeated bouts of high intensity exercise in association-football referees and assistant referees

SL Schmidt, GJ Schmidt, CS Padilla… - Frontiers in …, 2019 - frontiersin.org
Referees and assistant referees are submitted to high physical stress during matches.
Pressure to make decisions in front of large crowds is another potential stressor. These two …

Small peptide recognition sequence for intracellular sorting

KN Pandey - Current opinion in biotechnology, 2010 - Elsevier
Increasing evidence indicate that complex arrays of short signals and recognition peptide
sequence ensure accurate trafficking and distribution of transmembrane receptors and/or …

Cerebrospinal fluid biomarkers for dementia with lewy bodies

EB Mukaetova-Ladinska, R Monteith… - International Journal of …, 2010 - Wiley Online Library
More than 750,000 of the UK population suffer from some form of cognitive impairment and
dementia. Of these, 5–20% will have Dementia with Lewy Bodies (DLB). Clinico …

[HTML][HTML] Endocytosis and trafficking of natriuretic peptide receptor-a: potential role of short sequence motifs

KN Pandey - Membranes, 2015 - mdpi.com
The targeted endocytosis and redistribution of transmembrane receptors among membrane-
bound subcellular organelles are vital for their correct signaling and physiological functions …

[HTML][HTML] Attention deficits in Brazilian health care workers with chronic pain

SL Schmidt, IM Araguez, VV Neves… - Frontiers in …, 2022 - frontiersin.org
The impact of COVID-19 on chronic pain (CP) in non-infected vulnerable South American
subjects is unknown. Healthcare workers (HCWs) are at increased risk for CP. During the …