Heavy metals pose a serious threat if they go beyond permissible limits in our bodies. Much
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …

Abstract Heme oxygenase (HO)-1, the inducible isoform of the heme-degrading enzyme HO,
plays a critical role in inflammation and iron homeostasis. Regulatory functions of HO-1 are …

Heme oxygenase (HO)-1 is the inducible isoform of the first and rate-limiting enzyme of
heme degradation. Induction of HO-1 protects against the cytotoxicity of oxidative stress and …

Tissue-resident macrophages form an essential part of the first line of defense in all tissues
of the body. Next to their immunological role, they play an important role in maintaining …

To better understand the role of transcription factor NF-E2-related factor (NRF) 2 in the
human and its contribution to cancer chemoprevention, we have knocked down its negative …

Exercise is commonly prescribed as a lifestyle treatment for chronic metabolic diseases as it
functions as an insulin sensitizer, cardio-protectant, and essential lifestyle tool for effective …

Oxidative stress, perturbations in the cellular thiol level and redox balance, affects many
cellular functions, including signaling pathways. This, in turn, may cause the induction of …

Pancreatic cancer has the lowest survival rate among human cancers, and there are no
effective markers for its screening and early diagnosis. To identify genetic susceptibility …

Non-thermal atmospheric pressure plasma provides a novel therapeutic opportunity to
control redox-based processes, eg wound healing, cancer, and inflammatory diseases. By …

The regulation of gene expression in response to environmental signals and metabolic
imbalances is a key step in maintaining cellular homeostasis. BTB and CNC homology 1 …