Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Insights into human history from the first decade of ancient human genomics

Y Liu, X Mao, J Krause, Q Fu - Science, 2021 - science.org
Recent advancements in DNA sequencing technologies and laboratory preparation
protocols have rapidly expanded the scope of ancient DNA research over the past decade …

[HTML][HTML] The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Large-scale migration into Britain during the Middle to Late Bronze Age

N Patterson, M Isakov, T Booth, L Büster, CE Fischer… - Nature, 2022 - nature.com
Present-day people from England and Wales have more ancestry derived from early
European farmers (EEF) than did people of the Early Bronze Age 1. To understand this, here …

[HTML][HTML] Accurate detection of identity-by-descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick, I Olalde… - Nature Genetics, 2024 - nature.com
Long DNA segments shared between two individuals, known as identity-by-descent (IBD),
reveal recent genealogical connections. Here we introduce ancIBD, a method for identifying …

Origins and genetic legacy of prehistoric dogs

A Bergström, L Frantz, R Schmidt, E Ersmark… - Science, 2020 - science.org
Dogs were the first domestic animal, but little is known about their population history and to
what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that …

Getting genetic ancestry right for science and society

ACF Lewis, SJ Molina, PS Appelbaum, B Dauda… - Science, 2022 - science.org
Glaring health disparities have reinvigorated debate about the relevance of race to health,
including how race should and should not be used as a variable in research and …

Dairying, diseases and the evolution of lactase persistence in Europe

RP Evershed, G Davey Smith, M Roffet-Salque… - Nature, 2022 - nature.com
Abstract In European and many African, Middle Eastern and southern Asian populations,
lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over …

The genetic history of the Southern Arc: A bridge between West Asia and Europe

I Lazaridis, S Alpaslan-Roodenberg, A Acar, A Açıkkol… - Science, 2022 - science.org
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …

The genomic history of the Iberian Peninsula over the past 8000 years

I Olalde, S Mallick, N Patterson, N Rohland… - Science, 2019 - science.org
We assembled genome-wide data from 271 ancient Iberians, of whom 176 are from the
largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect …