Achieving superhigh sensitivity is the ultimate goal for bio-detection in modern analytical
science and life science. Among variable signal amplification strategies, nucleic acid …

Food safety is one of the biggest public issues occurring around the world. Microbiological,
chemical, and physical hazards can lead to food safety issues, which may occur at all stages …

The recent outbreak of novel coronavirus (SARS-CoV-2) causing COVID-19 disease
spreads rapidly in the world. Rapid and early detection of SARS-CoV-2 facilitates early …

CRISPR diagnostics based on nucleic acid amplification faces barriers to its commercial
use, such as contamination risks and insufficient sensitivity. Here, we propose a robust …

The 2019 novel coronavirus disease (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected all aspects of human life …

A recent outbreak of novel coronavirus (SARS-CoV-2), the causative agent of COVID-19,
has spread rapidly all over the world. Human immunodeficiency virus (HIV) is another …

The clustered regularly interspaced short palindromic repeats (CRISPR) system is a
promising platform for nucleic acid detection. Regulating the CRISPR reaction would be …

As a golden partner of recombinase polymerase amplification (RPA), CRISPR/Cas12a has
been proven to solve the false-positive problem caused by nonspecific amplification …

The clustered regularly interspaced short palindromic repeats (CRISPR)-based nucleic acid
detection can be combined with recombinase-aided amplification (RAA) to enable rapid …

Rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is critical for early diagnostics and timely medical treatment of coronavirus disease …