[HTML][HTML] Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

[HTML][HTML] Anisotropic 3D scaffolds for spinal cord guided repair: Current concepts

JPM Sousa, E Stratakis, J Mano, PAAP Marques - Biomaterials Advances, 2023 - Elsevier
A spinal cord injury (SCI) can be caused by unforeseen events such as a fall, a vehicle
accident, a gunshot, or a malignant illness, which has a significant impact on the quality of …

Transplantation of human bone marrow‐derived clonal mesenchymal stem cells reduces fibrotic scar formation in a rat spinal cord injury model

M Kim, KH Kim, SU Song, TG Yi… - Journal of Tissue …, 2018 - Wiley Online Library
This study aimed to evaluate the therapeutic effect on tissue repair and scar formation of
human bone marrow‐derived clonal mesenchymal stem cells (hcMSCs) homogeneously …

Fibroadhesive scarring of grafted collagen scaffolds interferes with implant–host neural tissue integration and bridging in experimental spinal cord injury

H Altinova, S Hammes, M Palm… - Regenerative …, 2019 - academic.oup.com
Severe traumatic spinal cord injury (SCI) results in a devastating and permanent loss of
function, and is currently an incurable condition. It is generally accepted that future …

Regenerative Potential of Platelet-Rich Fibrin Releasate Combined with Adipose Tissue–Derived Stem Cells in a Rat Sciatic Nerve Injury Model

MH Chuang, LH Ho, TF Kuo, SY Sheu… - Cell …, 2020 - journals.sagepub.com
Sciatic nerve injuries, not uncommon in trauma with a limited degree of functional recovery,
are considered a persistent clinical, social, and economic problem worldwide. Accumulating …

Dense fibroadhesive scarring and poor blood vessel-maturation hamper the integration of implanted collagen scaffolds in an experimental model of spinal cord injury

H Altinova, S Hammes, M Palm… - Biomedical …, 2020 - iopscience.iop.org
Severe spinal cord injury (SCI) results in permanent functional deficits, which despite pre-
clinical advances, remain untreatable. Combinational approaches, including the …

Cell‐enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix

AH Boecker, A Bozkurt, BS Kim… - Journal of tissue …, 2018 - Wiley Online Library
The reconstruction of peripheral nerve injuries is clinically challenging, and today, the
autologous nerve transplantation is still considered as the only gold standard remedy for …

种子细胞与生物支架在脊髓组织工程中的实验研究进展

漆国栋, 江琼, 伍亚民, 漆伟 - 中国康复理论与实践, 2021 - cjrtponline.com
种子细胞与生物支架在脊髓组织工程中的实验研究进展 Page 1 http://www.cjrtponline.com
2021年6月第27卷第6期 中国康复理论与实践 Chin J Rehabil Theory Pract, Jun., 2021, Vol. 27 …

Spinal cord injury

NN Madigan, AJ Windebank - Principles of Tissue Engineering, 2020 - Elsevier
The spinal cord has a limited potential to regenerate after traumatic injury, due to extensive
tissue destruction and a natural healing process, which creates physical, cellular, and …

[HTML][HTML] Characterization of a Novel Aspect of Tissue Scarring Following Experimental Spinal Cord Injury and the Implantation of Bioengineered Type-I Collagen …

H Altinova, P Achenbach, M Palm, I Katona… - International Journal of …, 2022 - mdpi.com
Numerous intervention strategies have been developed to promote functional tissue repair
following experimental spinal cord injury (SCI), including the bridging of lesion-induced …