Conquering the hypoxia limitation for photodynamic therapy

Y Wan, LH Fu, C Li, J Lin, P Huang - Advanced Materials, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …

Recent advances in functional nanomaterials for light–triggered cancer therapy

S Gai, G Yang, P Yang, F He, J Lin, D Jin, B Xing - Nano today, 2018 - Elsevier
Photo–triggered therapeutic modalities for cancer have attracted enormous attention in
recent years due to the easily focused and tuned properties of irradiation light that enable …

Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia

J Liu, W Bu, J Shi - Chemical reviews, 2017 - ACS Publications
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

[HTML][HTML] Development and application of hyaluronic acid in tumor targeting drug delivery

Z Luo, Y Dai, H Gao - Acta Pharmaceutica Sinica B, 2019 - Elsevier
Hyaluronic acid (HA) is a natural polysaccharide that has gained much attention due to its
biocompatibility, enzyme degradation capacity and active tumor targeting capacity. Its …

Graphene‐based smart platforms for combined Cancer therapy

Z Gu, S Zhu, L Yan, F Zhao, Y Zhao - Advanced Materials, 2019 - Wiley Online Library
The extensive research of graphene and its derivatives in biomedical applications during the
past few years has witnessed its significance in the field of nanomedicine. Starting from …

Functionalized graphene nanocomposites for enhancing photothermal therapy in tumor treatment

YW Chen, YL Su, SH Hu, SY Chen - Advanced drug delivery reviews, 2016 - Elsevier
Graphene and its derivatives have unique physical and chemical properties that make them
promising vehicles for photothermal therapy (PTT)-based cancer treatment. With intrinsic …

Type I photodynamic therapy by organic–inorganic hybrid materials: From strategies to applications

YY Wang, YC Liu, H Sun, DS Guo - Coordination Chemistry Reviews, 2019 - Elsevier
Photodynamic therapy (PDT) is a promising approach for treatment of cancer and bacterial
infection. Upon excitation by light, photosensitizers (PSs) produce reactive oxygen species …

Long-Circulating Au-TiO2 Nanocomposite as a Sonosensitizer for ROS-Mediated Eradication of Cancer

VG Deepagan, DG You, W Um, H Ko, S Kwon… - Nano …, 2016 - ACS Publications
Although sonodynamic therapy (SDT) has emerged as a potential alternative to
conventional photodynamic therapy, the low quantum yield of the sonosensitizer such as …

Marriage of scintillator and semiconductor for synchronous radiotherapy and deep photodynamic therapy with diminished oxygen dependence

C Zhang, K Zhao, W Bu, D Ni, Y Liu… - Angewandte Chemie …, 2015 - Wiley Online Library
Strong oxygen dependence and limited penetration depth are the two major challenges
facing the clinical application of photodynamic therapy (PDT). In contrast, ionizing radiation …

Combined photothermal and photodynamic therapy delivered by PEGylated MoS 2 nanosheets

T Liu, C Wang, W Cui, H Gong, C Liang, X Shi, Z Li… - Nanoscale, 2014 - pubs.rsc.org
Single-or few-layered transitional metal dichalcogenides, as a new genus of two-
dimensional nanomaterials, have attracted tremendous attention in recent years, owing to …