Application of diffusion tensor imaging (DTI) in the diagnosis of HIV-associated neurocognitive disorder (HAND): A meta-analysis and a system review

J Ma, X Yang, F Xu, H Li - Frontiers in Neurology, 2022 - frontiersin.org
Background The patients with HIV-associated neurocognitive disorder (HAND) are often
accompanied by white matter structure damage. Diffusion tensor imaging (DTI) is an …

Brain structure of perinatally HIV-infected patients on long-term treatment: A systematic review

M Van den Hof, AM Ter Haar, MWA Caan… - Neurology: Clinical …, 2019 - AAN Enterprises
Objective We aim to give an overview of the available evidence on brain structure and
function in PHIV-infected patients (PHIV+) using long-term combination antiretroviral therapy …

White matter abnormalities in children with HIV infection and exposure

M Jankiewicz, MJ Holmes, PA Taylor… - Frontiers in …, 2017 - frontiersin.org
Background: Due to changes in guidelines and access to treatment, more children start
combination antiretroviral therapy (ART) in infancy. With few studies examining the long …

Structural brain changes in perinatally HIV-infected young adolescents in South Africa

J Hoare, JP Fouche, N Phillips, JA Joska, L Myer… - Aids, 2018 - journals.lww.com
Objective: To describe the structural brain changes, neurocognitive and mental health
associations in adolescents perinatally infected with HIV-1 infection. Design: Cross …

Identifying the white matter impairments among ART-naïve HIV patients: a multivariate pattern analysis of DTI data

Z Tang, Z Liu, R Li, X Yang, X Cui, S Wang, D Yu… - European …, 2017 - Springer
Objective To identify the white matter (WM) impairments of the antiretroviral therapy (ART)-
naïve HIV patients by conducting a multivariate pattern analysis (MVPA) of Diffusion Tensor …

Cognitive outcomes at ages seven and nine years in South African children from the children with HIV early antiretroviral (CHER) trial: a longitudinal investigation

KS van Wyhe, B Laughton, MF Cotton… - Journal of the …, 2021 - Wiley Online Library
Introduction Many children living with HIV (CLWH) display impaired cognition. Although
early combination antiretroviral therapy (ART) produces improved cognitive outcomes, more …

Altered brain morphometry in 7-year old HIV-infected children on early ART

EC Nwosu, FC Robertson, MJ Holmes, MF Cotton… - Metabolic brain …, 2018 - Springer
Even with the increased roll out of combination antiretroviral therapy (cART), paediatric HIV
infection is associated with neurodevelopmental delays and neurocognitive deficits that may …

Neuroanatomical changes underlying vertical HIV infection in adolescents

X Yu, L Gao, H Wang, Z Yin, J Fang, J Chen… - Frontiers in …, 2019 - frontiersin.org
Purpose: The aim of this study was to investigate how human immunodeficiency virus (HIV)
affects brain development in adolescents, what are susceptible brain regions, and how …

Axonal chronic injury in treatment-naïve HIV+ adults with asymptomatic neurocognitive impairment and its relationship with clinical variables and cognitive status

R Li, J Sun, Z Tang, J Zhang, H Li - BMC neurology, 2018 - Springer
Background HIV is a neurotropic virus, and it can bring about neurodegeneration and may
even result in cognitive impairments. The precise mechanism of HIV-associated white matter …

[HTML][HTML] MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection

AS Graham, MJ Holmes, F Little, E Dobbels… - NeuroImage: Clinical, 2020 - Elsevier
The neurological changes in children living with perinatal HIV (PHIV) on antiretroviral
therapy (ART) can be studied at a metabolic level through proton magnetic resonance …