Anthocyanins Protect Against Ethanol-Induced Neuronal Apoptosis via GABAB1 Receptors Intracellular Signaling in Prenatal Rat Hippocampal Neurons

S ali Shah, I Ullah, HY Lee, MO Kim - Molecular neurobiology, 2013 - Springer
Here, we investigated the possible involvement of gamma-aminobutyric acid B1 receptor
(GABA B1 R) in mediating the protective effects of black soybean anthocyanins against …

Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons

I Ullah, N Ullah, MI Naseer, HY Lee, MOK Kim - BMC neuroscience, 2012 - Springer
Background Exposure to ethanol during early development triggers severe neuronal death
by activating multiple stress pathways and causes neurological disorders, such as fetal …

Anti-Neuroinflammatory Property of Phlorotannins from Ecklonia cava on Aβ25-35-Induced Damage in PC12 Cells

S Lee, K Youn, DH Kim, MR Ahn, E Yoon, OY Kim… - Marine drugs, 2018 - mdpi.com
Alzheimer disease (AD) is a neurodegenerative disorder characterized by excessive
accumulation of amyloid-beta peptide (Aβ) and progressive loss of neurons. Therefore, the …

Neuroprotective effect of osmotin against ethanol-induced apoptotic neurodegeneration in the developing rat brain

MI Naseer, I Ullah, ML Narasimhan, HY Lee… - Cell death & …, 2014 - nature.com
Fetal alcohol syndrome is a neurological and developmental disorder caused by exposure
of developing brain to ethanol. Administration of osmotin to rat pups reduced ethanol …

Vitamin C protects against ethanol and PTZ‐induced apoptotic neurodegeneration in prenatal rat hippocampal neurons

MI Naseer, N Ullah, I Ullah, PO Koh, HY Lee… - Synapse, 2011 - Wiley Online Library
Exposure to alcohol during brain development may cause a neurological syndrome called
fetal alcohol syndrome, characterized by pre‐and postnatal growth deficiencies, craniofacial …

γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2. 2) calcium channels by analgesic α-conotoxins

H Cuny, A De Faoite, TG Huynh, T Yasuda… - Journal of Biological …, 2012 - ASBMB
α-Conotoxins Vc1. 1 and RgIA are small peptides isolated from the venom of marine cone
snails. They have effective anti-nociceptive actions in rat models of neuropathic pain …

Antidotal effects of thymoquinone against neurotoxic agents

AR Sanati, T Farkhondeh… - Interdisciplinary …, 2018 - sciendo.com
Several plants which contain the active component thymoquinone (TQ) have been
traditionally used in herbal medicine to treat various diseases. Several studies indicated the …

Effects of pentoxifylline and H-89 on epileptogenic activity of bucladesine in pentylenetetrazol-treated mice

MS Hosseini-Zare, F Salehi, SY Seyedi, K Azami… - European journal of …, 2011 - Elsevier
The present study shows interactive effects of pentoxifylline (PTX) as a phosphodiesterase
(PDE) inhibitor, H-89 as a protein kinase A (PKA) inhibitor and bucladesine (db-cAMP) as a …

Investigation of compositional, structural, and dynamical changes of pentylenetetrazol-induced seizures on a rat brain by FT-IR spectroscopy

S Turker, G Ilbay, M Severcan, F Severcan - Analytical chemistry, 2014 - ACS Publications
To accomplish the appropriate treatment strategies of epilepsy action mechanisms
underlying epileptic seizures should be lightened. The identification of epileptic seizure …

Neuroprotective effect of vitamin C against the ethanol and nicotine modulation of GABAB receptor and PKA‐α expression in prenatal rat brain

MI Naseer, HY Lee, MO Kim - Synapse, 2010 - Wiley Online Library
Prenatal ethanol exposure has various deleterious effects on neuronal development and
can induce various defects in developing brain, resulting in fetal alcohol syndrome (FAS). γ …