[HTML][HTML] Oncolytic viruses—interaction of virus and tumor cells in the battle to eliminate cancer
A Howells, G Marelli, NR Lemoine, Y Wang - Frontiers in oncology, 2017 - frontiersin.org
Oncolytic viruses (OVs) are an emerging treatment option for many cancer types and have
recently been the focus of extensive research aiming to develop their therapeutic potential …
recently been the focus of extensive research aiming to develop their therapeutic potential …
[HTML][HTML] Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
YY Wu, TK Sun, MS Chen, M Munir… - Frontiers in Cellular and …, 2023 - frontiersin.org
Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer
therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis …
therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis …
[HTML][HTML] Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity
J Lin, S Sun, K Zhao, F Gao, R Wang, Q Li… - Nature …, 2023 - nature.com
The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly
killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis …
killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis …
Immune checkpoint blockade, immunogenic chemotherapy or IFN-α blockade boost the local and abscopal effects of oncolytic virotherapy
L Fend, T Yamazaki, C Remy, C Fahrner, M Gantzer… - Cancer research, 2017 - AACR
Athough the clinical efficacy of oncolytic viruses has been demonstrated for local treatment,
the ability to induce immune-mediated regression of distant metastases is still poorly …
the ability to induce immune-mediated regression of distant metastases is still poorly …
[HTML][HTML] Current trends in cancer immunotherapy
The search for an effective drug to treat oncological diseases, which have become the main
scourge of mankind, has generated a lot of methods for studying this affliction. It has also …
scourge of mankind, has generated a lot of methods for studying this affliction. It has also …
Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
JG Pol, S Levesque, ST Workenhe, S Gujar… - …, 2018 - Taylor & Francis
Oncolytic viruses selectively target and kill cancer cells in an immunogenic fashion, thus
supporting the establishment of therapeutically relevant tumor-specific immune responses …
supporting the establishment of therapeutically relevant tumor-specific immune responses …
[HTML][HTML] Development of oncolytic virotherapy: From genetic modification to combination therapy
Oncolytic virotherapy (OVT) is a novel form of immunotherapy using natural or genetically
modified viruses to selectively replicate in and kill malignant cells. Many genetically modified …
modified viruses to selectively replicate in and kill malignant cells. Many genetically modified …
Current understanding of reovirus oncolysis mechanisms
MB Phillips, JD Stuart, RM Rodríguez Stewart… - Oncolytic …, 2018 - Taylor & Francis
Mammalian orthoreovirus (reovirus) is under development as a cancer virotherapy. Clinical
trials demonstrate that reovirus-based therapies are safe and tolerated in patients with a …
trials demonstrate that reovirus-based therapies are safe and tolerated in patients with a …
[HTML][HTML] Oncolytic virotherapy in solid tumors: the challenges and achievements
KT Jin, WL Du, YY Liu, HR Lan, JX Si, XZ Mou - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic virotherapy (OVT) is a promising approach in cancer
immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without …
immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without …
[HTML][HTML] Oncolytic viruses and cancer, do you know the main mechanism?
W Kooti, H Esmaeili Gouvarchin Ghaleh… - Frontiers in …, 2021 - frontiersin.org
The global rate of cancer has increased in recent years, and cancer is still a threat to human
health. Recent developments in cancer treatment have yielded the understanding that …
health. Recent developments in cancer treatment have yielded the understanding that …