Liver biopsy in children: position paper of the ESPGHAN Hepatology Committee

A Dezsofi, U Baumann, A Dhawan… - Journal of pediatric …, 2015 - journals.lww.com
Liver biopsy (LB) is still the criterion standard procedure for obtaining liver tissue for
histopathological examination and a valuable tool in the diagnosis, prognosis, and …

[HTML][HTML] From immunosuppression to tolerance

DH Adams, A Sanchez-Fueyo, D Samuel - Journal of hepatology, 2015 - Elsevier
The past three decades have seen liver transplantation becoming a major therapeutic
approach in the management of end-stage liver diseases. This is due to the dramatic …

[HTML][HTML] 2016 comprehensive update of the Banff working group on liver allograft pathology: introduction of antibody-mediated rejection

AJ Demetris, C Bellamy, SG Hübscher, J O'leary… - American Journal of …, 2016 - Elsevier
The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature
evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France …

[HTML][HTML] De novo donor-specific HLA antibodies decrease patient and graft survival in liver transplant recipients

H Kaneku, JG O'leary, N Banuelos, LW Jennings… - American Journal of …, 2013 - Elsevier
The role of de novo donor-specific HLA antibodies (DSA) in liver transplantation remains
unknown as most of the previous studies have only focused on preformed HLA antibodies …

Efficacy and safety of immunosuppression withdrawal in pediatric liver transplant recipients: moving toward personalized management

S Feng, JC Bucuvalas, GV Mazariegos, JC Magee… - …, 2021 - Wiley Online Library
Background and Aims Tolerance is transplantation's holy grail, as it denotes allograft health
without immunosuppression and its toxicities. Our aim was to determine, among stable long …

[HTML][HTML] The role of donor-specific HLA alloantibodies in liver transplantation

JG O'leary, AJ Demetris, LS Friedman… - American Journal of …, 2014 - Elsevier
The impact of donor-specific HLA alloantibodies (DSA) on short-and long-term liver
transplant outcome is not clearly defined. While it is clear that not all levels of …

Evidence of chronic allograft injury in liver biopsies from long-term pediatric recipients of liver transplants

S Feng, JC Bucuvalas, AJ Demetris, BE Burrell… - Gastroenterology, 2018 - Elsevier
Background & Aims A substantial proportion of pediatric liver transplant recipients develop
subclinical chronic allograft injury. We studied whether there are distinct patterns of injury …

[HTML][HTML] Impact of IgG3 subclass and C1q-fixing donor-specific HLA alloantibodies on rejection and survival in liver transplantation

JG O'Leary, H Kaneku, N Banuelos… - American Journal of …, 2015 - Elsevier
Recent literature confirms donor-specific HLA alloantibodies (DSA) impair 5-year survival in
some but not all liver transplant recipients. In an effort to improve DSA testing's association …

Antibody-mediated rejection of the liver allograft: An update and a clinico-pathological perspective

BT Lee, MI Fiel, TD Schiano - Journal of hepatology, 2021 - Elsevier
Antibody-mediated rejection after liver transplantation is an under-recognised cause of
allograft injury. While definitions of acute and chronic antibody-mediated rejection have …

Non-invasive alloimmune risk stratification of long-term liver transplant recipients

J Vionnet, R Miquel, JG Abraldes, J Wall, E Kodela… - Journal of …, 2021 - Elsevier
Background & Aims Management of long-term immunosuppression following liver
transplantation (LT) remains empirical. Surveillance liver biopsies in combination with …