Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

A growing number of patients with Crohn's disease and ulcerative colitis have disease that is
refractory to multiple advanced therapies, have undergone multiple surgeries and require …

Background Tapinarof cream is a topical aryl hydrocarbon receptor–modulating agent under
investigation for the treatment of psoriasis. Tapinarof modulates the expression of interleukin …

Importance Once-daily roflumilast cream, 0.3%, a potent phosphodiesterase 4 inhibitor,
demonstrated efficacy and was well tolerated in a phase 2b trial of patients with psoriasis …

Background Tapinarof cream 1% once daily, an aryl hydrocarbon receptor-modulating
agent, was significantly more efficacious than vehicle and well tolerated in two 12-week …

Objective To provide guidance about management of psoriatic disease during the
coronavirus disease 2019 (COVID-19) pandemic. Study design A task force (TF) of 18 …

Psoriasis is a common chronic immune-mediated inflammatory skin disease with the
association of various comorbidities. Despite the introduction of highly effective biologic …

This study assesses the potential positive impact of a 0.05% isoxsuprine ointment on
psoriasiform skin inflammation generated by imiquimod in mouse models. Thirty-two male …

Background: Psoriasis is a chronic and immune-mediated inflammatory skin disease. Many
studies have shown that curcumin (CUR) has strong anti-inflammatory effects and can …

Topical formulation and delivery technologies for pharmaceutical application should
simultaneously address efficacy, safety and convenience of therapy. This has historically …