CA1 pyramidal cell diversity enabling parallel information processing in the hippocampus
I Soltesz, A Losonczy - Nature neuroscience, 2018 - nature.com
Hippocampal network operations supporting spatial navigation and declarative memory are
traditionally interpreted in a framework where each hippocampal area, such as the dentate …
traditionally interpreted in a framework where each hippocampal area, such as the dentate …
Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons
MS Cembrowski, N Spruston - Nature Reviews Neuroscience, 2019 - nature.com
The mechanistic operation of brain regions is often interpreted by partitioning constituent
neurons into 'cell types'. Historically, such cell types were broadly defined by their …
neurons into 'cell types'. Historically, such cell types were broadly defined by their …
Architecture of the mouse brain synaptome
F Zhu, M Cizeron, Z Qiu, R Benavides-Piccione… - Neuron, 2018 - cell.com
Synapses are found in vast numbers in the brain and contain complex proteomes. We
developed genetic labeling and imaging methods to examine synaptic proteins in individual …
developed genetic labeling and imaging methods to examine synaptic proteins in individual …
[HTML][HTML] Sublayer-specific coding dynamics during spatial navigation and learning in hippocampal area CA1
The mammalian hippocampus is critical for spatial information processing and episodic
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …
Spatial gene-expression gradients underlie prominent heterogeneity of CA1 pyramidal neurons
MS Cembrowski, JL Bachman, L Wang, K Sugino… - Neuron, 2016 - cell.com
Tissue and organ function has been conventionally understood in terms of the interactions
among discrete and homogeneous cell types. This approach has proven difficult in …
among discrete and homogeneous cell types. This approach has proven difficult in …
Dissociable structural and functional hippocampal outputs via distinct subiculum cell classes
MS Cembrowski, MG Phillips, SF DiLisio, BC Shields… - Cell, 2018 - cell.com
The mammalian hippocampus, comprised of serially connected subfields, participates in
diverse behavioral and cognitive functions. It has been postulated that parallel circuitry …
diverse behavioral and cognitive functions. It has been postulated that parallel circuitry …
Differential structure of hippocampal CA1 pyramidal neurons in the human and mouse
R Benavides-Piccione, M Regalado-Reyes… - Cerebral …, 2020 - academic.oup.com
Pyramidal neurons are the most common cell type and are considered the main output
neuron in most mammalian forebrain structures. In terms of function, differences in the …
neuron in most mammalian forebrain structures. In terms of function, differences in the …
Deep brain stimulation for Alzheimer's disease: stimulation parameters and potential mechanisms of action
Y Luo, Y Sun, X Tian, X Zheng, X Wang, W Li… - Frontiers in aging …, 2021 - frontiersin.org
Deep brain stimulation (DBS) is a neurosurgical technique that regulates neuron activity by
using internal pulse generators to electrodes in specific target areas of the brain. As a blind …
using internal pulse generators to electrodes in specific target areas of the brain. As a blind …
Teneurin-3 controls topographic circuit assembly in the hippocampus
Brain functions rely on specific patterns of connectivity. Teneurins are evolutionarily
conserved transmembrane proteins that instruct synaptic partner matching in Drosophila …
conserved transmembrane proteins that instruct synaptic partner matching in Drosophila …
Direct cortical inputs to hippocampal area CA1 transmit complementary signals for goal-directed navigation
JC Bowler, A Losonczy - Neuron, 2023 - cell.com
The subregions of the entorhinal cortex (EC) are conventionally thought to compute
dichotomous representations for spatial processing, with the medial EC (MEC) providing a …
dichotomous representations for spatial processing, with the medial EC (MEC) providing a …