Purpose of the Review To provide an up-to-date review of the incidence of stroke and large
vessel occlusion (LVO) around the globe, as well as the eligibility and access to IV …

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Background Trials of the efficacy and safety of endovascular thrombectomy in patients with
large ischemic strokes have been carried out in limited populations. Methods We performed …

Background Endovascular therapy for acute ischemic stroke is generally avoided when the
infarction is large, but the effect of endovascular therapy with medical care as compared with …

Background Trials of surgical evacuation of supratentorial intracerebral hemorrhages have
generally shown no functional benefit. Whether early minimally invasive surgical removal …

Importance Stroke is the fifth leading cause of death and a leading cause of disability in the
United States, affecting nearly 800 000 individuals annually. Observations Sudden …

Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Background Recent evidence suggests a beneficial effect of endovascular thrombectomy in
acute ischaemic stroke with large infarct; however, previous trials have relied on multimodal …

Background Trials examining the benefit of thrombectomy in anterior circulation proximal
large vessel occlusion stroke have enrolled patients considered to have salvageable brain …

Importance Advanced imaging for patient selection in mechanical thrombectomy is not
widely available. Objective To compare the clinical outcomes of patients selected for …