[HTML][HTML] Developmental pharmacokinetics of antibiotics used in neonatal ICU: focus on preterm infants

OI Butranova, EA Ushkalova, SK Zyryanov… - Biomedicines, 2023 - mdpi.com
Neonatal Infections are among the most common reasons for admission to the intensive
care unit. Neonatal sepsis (NS) significantly contributes to mortality rates. Empiric antibiotic …

[HTML][HTML] Physiologically based pharmacokinetic modeling in neonates: Current status and future perspectives

W Zhang, Q Zhang, Z Cao, L Zheng, W Hu - Pharmaceutics, 2023 - mdpi.com
Rational drug use in special populations is a clinical problem that doctors and pharma-cists
must consider seriously. Neonates are the most physiologically immature and vulnerable to …

A retrospective study on bile culture and antibiotic susceptibility patterns of patients with biliary tract infections

C Zhao, S Liu, X Bai, J Song, Q Fan… - Evidence‐Based …, 2022 - Wiley Online Library
Aim. This study aimed to provide profiles of microorganisms isolated from bile and antibiotic
susceptibility patterns of biliary tract infections (BTIs) in our center. Methods. A total of 277 …

[HTML][HTML] Circulating vitamin levels mediate the causal relationship between gut microbiota and cholecystitis: a two-step bidirectional Mendelian randomization study

C Miao, L Xiao, X Xu, S Huang, J Liu, K Chen - Frontiers in Nutrition, 2023 - frontiersin.org
Background The relationship between gut microbiota and the occurrence of cholecystitis
remains unclear. Existing research lacks a clear understanding of how circulating vitamin …

[HTML][HTML] Pathophysiological consequences and treatment strategy of obstructive jaundice

JJ Liu, YM Sun, Y Xu, HW Mei, W Guo… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Obstructive jaundice (OJ) is a common problem in daily clinical practice. However,
completely understanding the pathophysiological changes in OJ remains a challenge for …

[HTML][HTML] Management of intra-abdominal infections: recommendations by the Italian council for the optimization of antimicrobial use

M Sartelli, C Tascini, F Coccolini, F Dellai… - World Journal of …, 2024 - Springer
Intra-abdominal infections (IAIs) are common surgical emergencies and are an important
cause of morbidity and mortality in hospital settings, particularly if poorly managed. The …

Variability of bile bacterial profiles and drug resistance in patients with choledocholithiasis combined with biliary tract infection: a retrospective study

H Zhang, Y Cong, L Cao, K Xue, P Qi… - Gastroenterology …, 2024 - academic.oup.com
Background Biliary tract infection is a common complication of choledocholithiasis. This
study aimed to analyse the distribution of pathogenic bacteria in bile cultures from patients …

[HTML][HTML] Clinical presentation and incidence of anaerobic bacteria in surgically treated biliary tract infections and cholecystitis

J Strohäker, L Wiegand, C Beltzer, A Königsrainer… - Antibiotics, 2021 - mdpi.com
(1) Background: Cholecystitis and cholangitis are among the most common diseases treated
by general surgery. Gallstones lead to inflammation and bacterial infection of the biliary tract …

[HTML][HTML] Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: challenges and opportunities

L Gnatzy, G Ismailos, M Vertzoni, C Reppas - European Journal of …, 2023 - Elsevier
The term “intestinal dysbiosis” is used for indicating change (s) of the intestinal microbiota
which have been associated with the development of diseases and the deterioration of …

Pattern of bile cultures and antibiotic sensitivity tests in Sudanese patients diagnosed with obstructive jaundice: A single‐center prospective study

MS Babekir, EY Abdelrahim, WMA Doush… - JGH …, 2023 - Wiley Online Library
Abstract Background and Aim Biliary obstruction causes bacteriobilia and significant
morbidity and high mortality, which necessitates prompt and effective treatment for a good …