Cardiovascular risk assessment in rheumatoid arthritis: accelerated atherosclerosis, new biomarkers, and the effects of biological therapy

D Popescu, E Rezus, MC Badescu, N Dima… - Life, 2023 - mdpi.com
Rheumatoid arthritis (RA), one of the most common of the chronic inflammatory autoimmune
diseases (CIADs), is recognized as an independent cardiovascular risk factor. Traditional …

The predictive value of carotid ultrasonography with cardiovascular risk factors—A “SPIDER” promoting atherosclerosis

H Li, X Xu, B Luo, Y Zhang - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Insufficient recommendations do not support the clinical use of carotid ultrasonography for
further risk stratification in moderate-to-high risk patients with cardiovascular disease (CVD) …

Estimated 10-year cardiovascular risk in a large Italian cohort of rheumatoid arthritis patients: Data from the Cardiovascular Obesity and Rheumatic DISease (CORDIS …

F Cacciapaglia, FR Spinelli, M Piga, GL Erre… - European Journal of …, 2022 - Elsevier
Background Several cardiovascular (CV) risk algorithms are available to predict CV events
in the general population. However, their performance in patients with rheumatoid arthritis …

Combined use of QRISK3 and SCORE as predictors of carotid plaques in patients with rheumatoid arthritis

A Corrales, N Vegas-Revenga, B Atienza-Mateo… - …, 2021 - academic.oup.com
Objective Because carotid plaques predict the development of cardiovascular events in RA,
we aimed to assess if the combined use of the systematic coronary risk evaluation (SCORE) …

Subclinical carotid atherosclerosis in patients with rheumatoid arthritis at low cardiovascular risk

EV Gerasimova, TV Popkova, DA Gerasimova… - Biomedicines, 2023 - mdpi.com
Objective: To evaluate the rate of subclinical carotid atherosclerosis and clinical significance
of immunoinflammatory markers in patients with rheumatoid arthritis (RA) at low …

Interleukin 1 receptor antagonist relation to cardiovascular disease risk in patients with rheumatoid arthritis

C Almeida-Santiago, JC Quevedo-Abeledo… - Scientific Reports, 2022 - nature.com
Abstract Interleukin (IL) 1, and its family member, IL-1 receptor antagonist (IL-1ra), are
involved in the pathogenesis and inflammation perpetuation of patients with rheumatoid …

Diagnosis and management of cardiovascular risk in rheumatoid arthritis: main challenges and research agenda

F Atzeni, S Maiani, M Corda… - Expert Review of …, 2023 - Taylor & Francis
Introduction Rheumatoid arthritis (RA) exhibit a cardiovascular (CV) risk that is 1.5–2.0 times
higher compared to the general population. This CV risk excess is likely caused by the …

The angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis is disrupted in patients with rheumatoid arthritis

L de Armas-Rillo, JC Quevedo-Abeledo… - Arthritis Research & …, 2022 - Springer
Background Modulators of triglyceride metabolism include lipoprotein lipase (LPL),
angiopoietin-like protein 4 (ANGPTL4), and apolipoprotein C-3 (ApoC3). There is evidence …

Management of cardiovascular disease risk in rheumatoid arthritis

PH Dessein, MA Gonzalez-Gay - Journal of Clinical Medicine, 2022 - mdpi.com
Cardiovascular diseases, including ischemic heart disease and stroke, reportedly comprise
the top two causes of global mortality [1]. Eighty percent of cardiovascular events are …

The ratio of monocytes to HDL-cholesterol is associated with cardiovascular risk and insulin resistance in patients with rheumatoid arthritis

A Romo-Cordero, M González-Sierra… - Life, 2023 - mdpi.com
The monocytes to high-density lipoprotein (HDL)-cholesterol ratio (MHR) indicates
inflammation based on the anti-inflammatory properties of HDL-cholesterol as well as the …