Measures to prevent sexual mucosal transmission of human immunodeficiency virus (HIV)-1
are urgently needed to curb the growth of the acquired immunodeficiency syndrome (AIDS) …

While HIV-1 infection of target cells with cell-free viral particles has been largely
documented, intercellular transmission through direct cell-to-cell contact may be a …

Tunneling nanotubes are long, non-adherent F-actin-based cytoplasmic extensions which
connect proximal or distant cells and facilitate intercellular transfer. The identification of …

Viral infections spread based on the ability of viruses to overcome multiple barriers and
move from cell to cell, tissue to tissue, and person to person and even across species. While …

After host entry through mucosal surfaces, human immunodeficiency virus-1 (HIV-1)
disseminates to lymphoid tissues to establish a generalized infection of the immune system …

The interferon-induced transmembrane (IFITM) proteins protect cells from diverse virus
infections by inhibiting virus-cell fusion. IFITM proteins also inhibit HIV-1 replication through …

The life cycle of most viruses involves the release of particles into the extracellular space.
Consequently, the study of virus egress as well as virus entry has focused almost exclusively …

The virus HTLV-1 is thought to pass between cells through synapses formed when infected
lymphocytes make contact with other T cells. Isabelle Thoulouze and her colleagues …

Intercellular communication among cancer cells and their microenvironment is crucial to
disease progression. The mechanisms by which communication occurs between distant …

HIV is known to spread efficiently both in a cell-free state and from cell to cell, however the
relative importance of the cell-cell transmission mode in natural infection has not yet been …