Targeting cell signaling in allergic asthma
SS Athari - Signal transduction and targeted therapy, 2019 - nature.com
Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …
Macrophage polarization and allergic asthma
Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …
Macrophage polarization has been shown to have a profound impact on asthma …
MiRNA-mediated macrophage polarization and its potential role in the regulation of inflammatory response
Monocytes and macrophages are important components of the immune system, specialized
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …
Emerging role of microRNA-21 in cancer
YH Feng, CJ Tsao - Biomedical reports, 2016 - spandidos-publications.com
MicroRNAs (miRs) are a class of single-stranded RNA molecules of 15-27 nucleotides in
length that regulate gene expression at the post-translational level. miR-21 is one of the …
length that regulate gene expression at the post-translational level. miR-21 is one of the …
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …
Spotlight on microRNAs in allergy and asthma
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …
Glioblastoma-associated microglia reprogramming is mediated by functional transfer of extracellular miR-21
Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in
the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their …
the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their …
Turning 21: induction of miR-21 as a key switch in the inflammatory response
FJ Sheedy - Frontiers in immunology, 2015 - frontiersin.org
miR-21 is one of the most highly expressed members of the small non-coding microRNA
family in many mammalian cell types. Its expression is further enhanced in many diseased …
family in many mammalian cell types. Its expression is further enhanced in many diseased …
Physiological and pathological roles for microRNAs in the immune system
Mammalian microRNAs (miRNAs) have recently been identified as important regulators of
gene expression, and they function by repressing specific target genes at the post …
gene expression, and they function by repressing specific target genes at the post …
Extracellular vesicles: novel communicators in lung diseases
The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …
perceivable that the endothelium of the lung contributes significantly to the circulation of …