[HTML][HTML] Prostate cancer review: genetics, diagnosis, treatment options, and alternative approaches

M Sekhoacha, K Riet, P Motloung, L Gumenku… - Molecules, 2022 - mdpi.com
Simple Summary Prostate cancer affects men of all racial and ethnic groups and leads to
higher rates of mortality in those belonging to a lower socioeconomic status due to late …

[HTML][HTML] Triclosan: A small molecule with controversial roles

MS Sinicropi, D Iacopetta, J Ceramella, A Catalano… - Antibiotics, 2022 - mdpi.com
Triclosan (TCS), a broad-spectrum antimicrobial agent, has been widely used in personal
care products, medical products, plastic cutting boards, and food storage containers …

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhang, AM Lee, S Jena, Y Huang… - Proceedings of the …, 2023 - National Acad Sciences
Prostate cancer (PC) is the most frequently diagnosed malignancy and a leading cause of
cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic …

[HTML][HTML] Epithelial-to-mesenchymal transition-related markers in prostate cancer: From bench to bedside

S Gogola, M Rejzer, HF Bahmad, W Abou-Kheir… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) is the second most frequent type of cancer in men
worldwide. Treatment options for early-stage PCa include external beam radiation therapy …

[HTML][HTML] Drug repurposing in non-small cell lung carcinoma: old solutions for new problems

G Doumat, D Daher, MB Zerdan, N Nasra… - Current …, 2023 - mdpi.com
Lung cancer is the second most common cancer and the leading cause of cancer-related
deaths in 2022. The majority (80%) of lung cancer cases belong to the non-small cell lung …

[HTML][HTML] Pharmacological efficacy of repurposing drugs in the treatment of prostate cancer

T Lourenço, N Vale - International Journal of Molecular Sciences, 2023 - mdpi.com
Worldwide, prostate cancer (PC) is the second most frequent cancer among men and the
fifth leading cause of death; moreover, standard treatments for PC have several issues, such …

[HTML][HTML] Drug repurposing to enhance antitumor response to PD-1/PD-L1 immune checkpoint inhibitors

X Thuru, R Magnez, H El-Bouazzati, G Vergoten… - Cancers, 2022 - mdpi.com
Simple Summary Novel pharmacological approaches are needed to improve treatments of
advanced cancers, despite the considerable benefit of immunotherapy. New drugs are …

[HTML][HTML] Current trends and future prospects of drug repositioning in gastrointestinal oncology

N Fatemi, M Karimpour, H Bahrami, MR Zali… - Frontiers in …, 2024 - frontiersin.org
Gastrointestinal (GI) cancers comprise a significant number of cancer cases worldwide and
contribute to a high percentage of cancer-related deaths. To improve survival rates of GI …

[HTML][HTML] Identification of Promising Drug Candidates against Prostate Cancer through Computationally-Driven Drug Repurposing

L Bernal, L Pinzi, G Rastelli - International Journal of Molecular Sciences, 2023 - mdpi.com
Prostate cancer (PC) is one of the most common types of cancer in males. Although early
stages of PC are generally associated with favorable outcomes, advanced phases of the …

[HTML][HTML] Target repositioning using multi-layer networks and machine learning: the case of prostate cancer.

M Picard, MP Scott-Boyer, A Bodein, M Leclercq… - Computational and …, 2024 - Elsevier
The discovery of novel therapeutic targets, defined as proteins which drugs can interact with
to induce therapeutic benefits, typically represent the first and most important step of drug …