Macrophages contribute to Ebola virus disease through their susceptibility to direct infection,
their multi-faceted response to ebolaviruses, and their association with pathological findings …

Outbreaks of Ebola ebolavirus (EBOV) have been associated with high morbidity and
mortality. Milestones have been reached recently in the management of EBOV disease …

Ebola virus (EBOV) disease is marked by rapid virus replication and spread. EBOV enters
the cell by macropinocytosis and replicates in the cytoplasm, and nascent virions egress …

Coronavirus disease 2019 (COVID-19) has been a pandemic for the past two years.
Predicting patient prognosis is critical. Although immune checkpoints (ICs) were shown to be …

Marburg virus (MARV) VP40 protein (mVP40) directs egress and spread of MARV, in part, by
recruiting specific host WW domain-containing proteins via its conserved PPxY late (L) …

Fermented foods have long been known to have immunomodulatory capabilities, and
fermentates derived from the lactic acid bacteria of dairy products can modulate the immune …

Macrophages are critical in the pathogenesis of a diverse group of viral pathogens, both as
targets of infection and for eliciting primary defense mechanisms. Our prior in vitro work …

Sudan virus (SUDV) is one of five filoviruses that compose the genus Ebolavirus that has
been responsible for episodic outbreaks in Central Africa. While the SUDV glycoprotein (GP) …

Ebola virus disease (EVD) represents a global health threat. The etiological agents of EVD
are 6 species of Orthoebolaviruses, with Orthoebolavirus zairense (EBOV) having the …

Marburg virus (MARV) VP40 protein (mVP40) directs egress and spread of MARV, in part, by
recruiting specific host WW-domain containing proteins via its conserved PPxY Late (L) …