More than one and a half centuries ago, adverse human health effects were reported after
use of a cadmium-containing silver polishing agent. Long-term cadmium exposure gives rise …

Besides being important occupational hazards, lead and cadmium are nowadays metals of
great environmental concern. Both metals, without any physiological functions, can induce …

Humans are exposed to a significant number of chemicals that are suspected to produce
disturbances in hormone homeostasis. Hence, in recent decades, there has been a growing …

The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …

Cadmium (Cd) and lead (Pb) are toxic heavy metals that cause adverse health effects in
humans and animals. Chelation therapy, the conventional treatment for heavy metal toxicity …

The first health effects of cadmium (Cd) were reported already in 1858. Respiratory and
gastrointestinal symptoms occurred among persons using Cd-containing polishing agent …

Despite many scientific advances, human exposure to, and intoxication by, toxic metal
species continues to occur. Surprisingly, little is understood about the mechanisms by which …

Cadmium (Cd) is an industrial and environmental pollutant that affects adversely a number
of organs in humans and other mammals, including the kidneys, liver, lungs, pancreas …

Methylmercury is a widely distributed environmental toxicant with detrimental effects on the
developing and adult nervous system. Due to its accumulation in the food chain, chronic …

Metallothioneins are cysteine-rich, small metal-binding proteins present in various
mammalian tissues. Of the four common metallothioneins, MT-1 and MT-2 (MTs) are …