Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Vascular cognitive impairment

WM Van Der Flier, I Skoog, JA Schneider… - Nature reviews Disease …, 2018 - nature.com
The term vascular cognitive impairment (VCI) was introduced around the start of the new
millennium and refers to the contribution of vascular pathology to any severity of cognitive …

Reproducibility of real-world evidence studies using clinical practice data to inform regulatory and coverage decisions

SV Wang, SK Sreedhara, S Schneeweiss - Nature communications, 2022 - nature.com
Studies that generate real-world evidence on the effects of medical products through
analysis of digital data collected in clinical practice provide key insights for regulators …

Assessment and management of behavioral and psychological symptoms of dementia

HC Kales, LN Gitlin, CG Lyketsos - Bmj, 2015 - bmj.com
Behavioral and psychological symptoms of dementia include agitation, depression, apathy,
repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of …

Cumulative head impact exposure predicts later-life depression, apathy, executive dysfunction, and cognitive impairment in former high school and college football …

PH Montenigro, ML Alosco, BM Martin… - Journal of …, 2017 - liebertpub.com
The term “repetitive head impacts”(RHI) refers to the cumulative exposure to concussive and
subconcussive events. Although RHI are believed to increase risk for later-life neurological …

The American Psychiatric Association practice guideline on the use of antipsychotics to treat agitation or psychosis in patients with dementia

VI Reus, LJ Fochtmann, AE Eyler… - American Journal of …, 2016 - Am Psychiatric Assoc
The goal of this guideline is to improve the care of patients with dementia who are exhibiting
agitation or psychosis. More specifically, this guideline focuses on the judicious use of …

Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm

DT Maust, HM Kim, LS Seyfried, C Chiang… - JAMA …, 2015 - jamanetwork.com
Importance Antipsychotic medications are associated with increased mortality in older adults
with dementia, yet their absolute effect on risk relative to no treatment or an alternative …

Prevention and management of delirium in the intensive care unit

MF Mart, SW Roberson, B Salas… - … in respiratory and …, 2021 - thieme-connect.com
Delirium is a debilitating form of brain dysfunction frequently encountered in the intensive
care unit (ICU). It is associated with increased morbidity and mortality, longer lengths of stay …

Meta-analysis of nonpharmacological interventions for neuropsychiatric symptoms of dementia

H Brodaty, C Arasaratnam - American Journal of Psychiatry, 2012 - Am Psychiatric Assoc
Objective Behavioral and psychological symptoms are common in dementia, and they are
especially stressful for family caregivers. Nonpharmacological (or psychosocial) …

Postoperative delirium: acute change with long-term implications

JL Rudolph, ER Marcantonio - Anesthesia & Analgesia, 2011 - journals.lww.com
Delirium is an acute change in cognition and attention, which may include alterations in
consciousness and disorganized thinking. Although delirium may affect any age group, it is …