The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

Electrospray ionization mass spectrometry (ESI-MS) is nowadays one of the cornerstones of
biomolecular mass spectrometry and proteomics. Advances in sample preparation and …

Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

The field of ion mobility-mass spectrometry (IM-MS) has grown with significant momentum in
recent years in both fundamental advances and pioneering applications. A search of the …

Ion mobility mass spectrometry (IM-MS) allows the structural interrogation of biomolecules
by reporting their collision cross sections (CCSs). The major bottleneck for exploiting IM-MS …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

Ion mobility (IM) separations have a broad range of analytical applications, but insufficient
resolution often limits their utility. Here, we report on ion mobility separations in a structures …

The size and shape of peptide ions in the gas phase are an under-explored dimension for
mass spectrometry-based proteomics. To investigate the nature and utility of the peptide …

Native mass spectrometry (MS) is aimed at preserving and determining the native structure,
composition, and stoichiometry of biomolecules and their complexes from solution after they …