Paraoxonases (PONs) are a family of hydrolytic enzymes consisting of three members,
PON1, PON2, and PON3, located on human chromosome 7. Identifying the physiological …

Spanning three decades in research, Paraoxonases (PON1) carried potential of dealing with
neurotoxicity of organophosphates entering the circulation and preventing cholinergic crisis …

Phosphate ester hydrolysis is fundamental to many life processes, and has been the topic of
substantial experimental and computational research effort. However, even the simplest of …

Human serum paraoxonase-1 (PON1) is an important hydrolase-type enzyme found in
numerous tissues. Notably, it can exist in two isozyme-forms, Q and R, that exhibit different …

Abstract Serum paraoxonase1 (PON1) has special function in human body organism
including the antioxidant and anti-atherogenic properties. In the present study, the effect of …

Lactones are prevalent in biological and industrial settings, yet there is a lack of information
regarding enzymes used to metabolize these compounds. One compound, γ-valerolactone …

Serum paraoxonase 1 (PON1) is a calcium-dependent enzyme that can catalyze the
hydrolysis of multiple substrates, including lactones, thiolactones, carbonates, esters and …

Many bacterial species exhibit cell-density dependent traits that are most advantageous
when expressed simultaneously throughout their population. Examples of these traits …

Abstract Paraoxonase 1 (PON1) is an enzyme synthesised in the liver that is associated with
High Density Lipoprotein (HDL) and increasingly with a number of human diseases …