Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Virus–receptor interactions play a key regulatory role in viral host range, tissue tropism, and
viral pathogenesis. Viruses utilize elegant strategies to attach to one or multiple receptors …

Emerging evidence suggests that host glycans influence severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain …

Highlights•Most mammalian virus families use cell-surface glycans as receptors.•Glycan
receptors are diverse in structure and distribution, giving rise to species and tissue …

The human polyomavirus, JCPyV, is the causative agent of progressive multifocal
leukoencephalopathy (PML) in immunosuppressed and immunomodulated patients. Initial …

The endemic human JC polyomavirus (JCPyV) causes progressive multifocal
leukoencephalopathy in immune-suppressed patients. The mechanisms of virus infection in …

In the fifty years since the discovery of JC polyomavirus (JCPyV), the body of research
representing our collective knowledge on this virus has grown substantially. As the …

JC polyomavirus (JCPyV) is the causative agent of a fatal central nervous system
demyelinating disease known as progressive multifocal leukoencephalopathy (PML). PML …

The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS),
including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient …

Glioblastoma multiforme (GBM), the most common malignant brain tumor, has a short period
of survival even with recent multimodality treatment. The neurotropic JC polyomavirus …