Engineered microenvironments provide new insights into ovarian and prostate cancer progression and drug responses

D Loessner, BM Holzapfel, JA Clements - Advanced drug delivery reviews, 2014 - Elsevier
Tissue engineering technologies, which have originally been designed to reconstitute
damaged tissue structure and function, can mimic not only tissue regeneration processes …

Mesenchymal stem/stromal cells in liver fibrosis: recent findings, old/new caveats and future perspectives

EJ Fiore, G Mazzolini, JB Aquino - Stem Cell Reviews and Reports, 2015 - Springer
Mesenchymal stem/stromal cells (MSCs) are progenitors which share plastic-adherence
capacity and cell surface markers but have different properties according to their cell and …

CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells

K Arndt, T Grinenko, N Mende… - Proceedings of the …, 2013 - National Acad Sciences
Pentatransmembrane glycoprotein prominin-1 (CD133) is expressed at the cell surface of
multiple somatic stem cells, and it is widely used as a cell surface marker for the isolation …

CD133-positive hematopoietic stem cells: from biology to medicine

R Handgretinger, S Kuçi - Prominin-1 (CD133): New Insights on Stem & …, 2013 - Springer
Lifelong hematopoiesis is sustained by a very small number of hematopoietic stem cells
capable of self-renewal and differentiation into multiple hematopoietic lineages. The …

Multimodal delivery of isogenic mesenchymal stem cells yields synergistic protection from retinal degeneration and vision loss

B Bakondi, S Girman, B Lu… - Stem cells translational …, 2017 - academic.oup.com
We previously demonstrated that subretinal injection (SRI) of isogenic mesenchymal stem
cells (MSCs) reduced the severity of retinal degeneration in Royal College of Surgeons rats …

Stem and progenitor cells for neurological repair: Minor issues, major hurdles, and exciting opportunities for paracrine‐based therapeutics

IS Shimada, JL Spees - Journal of Cellular Biochemistry, 2011 - Wiley Online Library
The transplantation of cultured stem and progenitor cells is a key element in the rapidly
growing field of regenerative medicine. Based on their ability to rescue and/or repair injured …

Acetate supplementation induces growth arrest of NG2/PDGFRα-positive oligodendroglioma-derived tumor-initiating cells

PM Long, SW Tighe, HE Driscoll, JR Moffett… - PLoS …, 2013 - journals.plos.org
Cancer is associated with globally hypoacetylated chromatin and considerable attention has
recently been focused on epigenetic therapies. N-acetyl-L-aspartate (NAA), the primary …

Contribution of bone marrow-derived cells to in situ engineered tissue capsules in a rat model of chronic kidney disease

T Bezhaeva, WJ Geelhoed, D Wang, H Yuan… - Biomaterials, 2019 - Elsevier
Tissue engineered blood vessels (TEBVs) hold great promise for clinical use in patients with
end stage renal disease (ESRD) requiring vascular access for hemodialysis. A promising …

[HTML][HTML] Amniotic fluid stem cells in a bone microenvironment: driving host angiogenic response

T Mirabella, C Gentili, A Daga, R Cancedda - Stem Cell Research, 2013 - Elsevier
The repair of skeletal defects remains a substantial economic and biomedical burden. The
extra-embryonic fetal stem cells derived from amniotic fluid (AFSCs) have been used for the …

Prominin-1 (CD133) and the cell biology of neural progenitors and their progeny

AM Sykes, WB Huttner - Prominin-1 (CD133): New Insights on Stem & …, 2013 - Springer
Our group discovered prominin-1 in search for markers to study the cell polarity of neural
stem and progenitor cells in the developing brain. Over the past 15 years, prominin-1, also …