Antidepressant and anxiolytic effects of activating 5HT2A receptors in the anterior cingulate cortex and the theoretical mechanisms underlying them–A scoping review …

L Miranda - Brain Research, 2024 - Elsevier
Psychedelic drugs that activate the 5HT2A receptor have long been the target of extensive
clinical research, particularly in models of psychiatric illness. The aim of this literature review …

The glutamate hypothesis of schizophrenia: neuroimaging and drug development

A Egerton, J M. Stone - Current pharmaceutical biotechnology, 2012 - benthamdirect.com
Over the last 50 years, evidence for central involvement of glutamatergic neurotransmission
in the pathophysiology of schizophrenia has accumulated. Recent advances in …

The therapeutic potential of the cerebellum in schizophrenia

KL Parker, NS Narayanan… - Frontiers in systems …, 2014 - frontiersin.org
The cognitive role of the cerebellum is critically tied to its distributed connections throughout
the brain. Accumulating evidence from anatomical, structural and functional imaging, and …

Common and specific functional activity features in schizophrenia, major depressive disorder, and bipolar disorder

Y Yang, S Liu, X Jiang, H Yu, S Ding, Y Lu, W Li… - Frontiers in …, 2019 - frontiersin.org
Objectives: Schizophrenia (SZ), major depressive disorder (MDD), and bipolar disorder (BD)
are serious mental disorders with distinct diagnostic criteria. They share common clinical …

Disrupted brain anatomical connectivity in medication-naïve patients with first-episode schizophrenia

R Zhang, Q Wei, Z Kang, A Zalesky, M Li, Y Xu… - Brain Structure and …, 2015 - Springer
Previous studies suggested that the topological properties of brain anatomical networks may
be aberrant in schizophrenia (SCZ), and most of them focused on the chronic and …

A self-training deep neural network for early prediction of cognitive deficits in very preterm infants using brain functional connectome data

R Ali, H Li, JR Dillman, M Altaye, H Wang, NA Parikh… - Pediatric …, 2022 - Springer
Background Deep learning has been employed using brain functional connectome data for
evaluating the risk of cognitive deficits in very preterm infants. Although promising, training …

Cognitive and neural strategies during control of the anterior cingulate cortex by fMRI neurofeedback in patients with schizophrenia

JS Cordes, KA Mathiak, M Dyck, EM Alawi… - Frontiers in behavioral …, 2015 - frontiersin.org
Cognitive functioning is impaired in patients with schizophrenia, leading to significant
disabilities in everyday functioning. Its improvement is an important treatment target …

Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume

C Tapias-Espinosa, C Río-Álamos… - …, 2019 - nature.com
Prepulse inhibition (PPI) of startle response is a measure of sensorimotor gating that is
impaired in schizophrenia and in many other clinical conditions. Rat models using …

Functional and anatomical connectivity abnormalities in cognitive division of anterior cingulate cortex in schizophrenia

H Yan, L Tian, J Yan, W Sun, Q Liu, YB Zhang, XM Li… - 2012 - journals.plos.org
Introduction Current pathophysiological theories of schizophrenia highlight the role of
altered brain functional and anatomical connectivity. The cognitive division of anterior …

Brain glutamate concentration in men with early psychosis: a magnetic resonance spectroscopy case–control study at 7 T

BR Godlewska, A Minichino, U Emir… - Translational …, 2021 - nature.com
Abnormalities in glutamate neurotransmission are linked to psychotic symptoms and
cognitive dysfunction in schizophrenia. magnetic resonance spectroscopy (MRS) provides …