Isolation, separation, and preconcentration of biologically active compounds from plant matrices by extraction techniques

V Raks, H Al-Suod, B Buszewski - Chromatographia, 2018 - Springer
Abstract Development of efficient methods for isolation and separation of biologically active
compounds remains an important challenge for researchers. Designing systems such as …

Enzymes in the time of COVID‐19: An overview about the effects in the human body, enzyme market, and perspectives for new drugs

LXSGM Fe, EP Cipolatti, MCC Pinto… - Medicinal Research …, 2022 - Wiley Online Library
The rising pandemic caused by a coronavirus, resulted in a scientific quest to discover some
effective treatments against its etiologic agent, the severe acute respiratory syndrome …

Preparation of core–shell polymer supports to immobilize lipase B from Candida antarctica: effect of the support nature on catalytic properties

AG Cunha, MD Besteti, EA Manoel, AAT da Silva… - Journal of Molecular …, 2014 - Elsevier
Core–shell supports have been prepared and utilized to immobilize lipase B from Candida
antarctica. The hydrophobic nature of the supports permitted to immobilize the enzyme via …

Synthesis of lipase/silica biocatalysts through the immobilization of CALB on porous SBA-15 and their application on the resolution of pharmaceutical derivatives and …

EP Cipolatti, NS Rios, JS Sousa, J de Macedo Robert… - Molecular …, 2021 - Elsevier
A recombinant lipase from Candida antarctica, LIPB, was obtained through fermentation
using an alternative low-cost medium and immobilized on the distinct mesoporous silica …

Evaluation of the performance of differently immobilized recombinant lipase B from Candida antarctica preparations for the synthesis of pharmacological derivatives in …

EA Manoel, JM Robert, MCC Pinto, ACO Machado… - RSC …, 2016 - pubs.rsc.org
This paper shows the production of lipase B from Candida antarctica (LIPB) after cloning the
gene that encoded it in Pichia pastoris using PGK as a constitutive promoter. The production …

Lipase Regioselective O‐Acetylations of a myo‐Inositol Derivative: Efficient Desymmetrization of 1,3‐Di‐O‐benzyl‐myo‐inositol

MFP Ribeiro, KC Pais, BSM de Jesus… - European Journal of …, 2018 - Wiley Online Library
Chiral myo‐inositol derivatives play key roles in cell‐signaling processes. Despite the
relevance of these compounds, few syntheses of them rely on enantioselective catalytic …

Factors screening to statistical experimental design of racemic atenolol kinetic resolution via transesterification reaction in organic solvent using free Pseudomonas …

J Agustian, AH Kamaruddin, HY Aboul‐Enein - Chirality, 2017 - Wiley Online Library
As the (R)‐enantiomer of racemic atenolol has no β‐blocking activity and no lack of side
effects, switching from the racemate to the (S)‐atenolol is more favorable. Transesterification …

Biocatalysis in organic media

A Illanes - 2015 - books.rsc.org
3.1 E nzyme Structure and Function each one of the chemical reactions of cell metabolism in
all living forms is catalyzed by an enzyme. enzymes are quite evolved forms of catalysts that …

Efficient desymmetrization of 4, 6-di-O-benzyl-myo-inositol by Lipozyme TL-IM

MG Vasconcelos, RHC Briggs, LCS Aguiar… - Carbohydrate …, 2014 - Elsevier
The enantioselective enzymatic desymmetrization of 4, 6-di-O-benzyl-myo-inositol, a myo-
inositol derivative, was effectively catalyzed by Thermomyces lanuginosus lipase (TL-IM) …