Invasive lobular carcinoma of the breast: morphology, biomarkers and'omics
AEMC Reed, JR Kutasovic, SR Lakhani… - Breast cancer …, 2015 - Springer
Invasive lobular carcinoma of the breast is the most common 'special'morphological subtype
of breast cancer, comprising up to 15% of all cases. Tumours are generally of a good …
of breast cancer, comprising up to 15% of all cases. Tumours are generally of a good …
Biological determinants of endocrine resistance in breast cancer
EA Musgrove, RL Sutherland - Nature Reviews Cancer, 2009 - nature.com
Endocrine therapies targeting oestrogen action (anti-oestrogens, such as tamoxifen, and
aromatase inhibitors) decrease mortality from breast cancer, but their efficacy is limited by …
aromatase inhibitors) decrease mortality from breast cancer, but their efficacy is limited by …
Relative effectiveness of letrozole compared with tamoxifen for patients with lobular carcinoma in the BIG 1-98 trial
O Metzger Filho, A Giobbie-Hurder, E Mallon… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To evaluate the relative effectiveness of letrozole compared with tamoxifen for
patients with invasive ductal or lobular carcinoma. Patients and Methods Patients diagnosed …
patients with invasive ductal or lobular carcinoma. Patients and Methods Patients diagnosed …
Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond
Oestrogen-related receptors (ERRs) are orphan nuclear receptors that were initially
investigated in breast cancer because of their structural relationship to oestrogen receptors …
investigated in breast cancer because of their structural relationship to oestrogen receptors …
Differences between invasive lobular and invasive ductal carcinoma of the breast: results and therapeutic implications
R Barroso-Sousa… - Therapeutic advances in …, 2016 - journals.sagepub.com
Invasive lobular carcinoma (ILC) is the second most common histologic subtype of breast
cancer (BC): ILC differs from invasive ductal carcinoma (IDC) in its clinicopathological …
cancer (BC): ILC differs from invasive ductal carcinoma (IDC) in its clinicopathological …
Comprehensive review of molecular mechanisms and clinical features of invasive lobular cancer
Invasive lobular carcinoma (ILC) accounts for 10% to 15% of breast cancers in the United
States, 80% of which are estrogen receptor (ER)-positive, with an unusual metastatic pattern …
States, 80% of which are estrogen receptor (ER)-positive, with an unusual metastatic pattern …
The RNA-binding protein Sam68 is a multifunctional player in human cancer
P Bielli, R Busà, MP Paronetto… - Endocrine-related …, 2011 - erc.bioscientifica.com
Resistance to chemotherapy is a major complication in the treatment of advanced breast
cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer …
cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer …
Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1-and estrogen receptor-containing transcription complexes
Progesterone and estrogen are important drivers of breast cancer proliferation. Herein, we
probed estrogen receptor-α (ER) and progesterone receptor (PR) cross-talk in breast cancer …
probed estrogen receptor-α (ER) and progesterone receptor (PR) cross-talk in breast cancer …
Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response
Invasive lobular carcinoma (ILC) is a histologic subtype of breast cancer that is frequently
associated with favorable outcomes, as approximately 90% of ILC express the estrogen …
associated with favorable outcomes, as approximately 90% of ILC express the estrogen …
ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation
Estrogen receptor alpha (ER/ESR1) is frequently mutated in endocrine resistant ER-positive
(ER+) breast cancer and linked to ligand-independent growth and metastasis. Despite the …
(ER+) breast cancer and linked to ligand-independent growth and metastasis. Despite the …