The interplay of inflammation and remyelination: rethinking MS treatment with a focus on oligodendrocyte progenitor cells

O Zveik, A Rechtman, T Ganz… - Molecular …, 2024 - Springer
Background Multiple sclerosis (MS) therapeutic goals have traditionally been dichotomized
into two distinct avenues: immune-modulatory-centric interventions and pro-regenerative …

Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer

Y Jiang, Y Wang, G Chen, F Sun, Q Wu, Q Huang… - Cell Metabolism, 2024 - cell.com
Immune checkpoint blockade has led to breakthroughs in the treatment of advanced gastric
cancer. However, the prominent heterogeneity in gastric cancer, notably the heterogeneity of …

[HTML][HTML] Synovial fluid extracellular vesicles as arthritis biomarkers: the added value of lipid-profiling and integrated omics

L Varela, CHA van de Lest… - Extracellular Vesicles …, 2024 - oaepublish.com
Arthritis, a diverse group of inflammatory joint disorders, poses great challenges in early
diagnosis and targeted treatment. Timely intervention is imperative, yet conventional …