Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues
The progression of chronic liver diseases (CLD), irrespective of etiology, involves chronic
parenchymal injury, persistent activation of inflammatory response as well as sustained …
parenchymal injury, persistent activation of inflammatory response as well as sustained …
Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
The role of intestinal permeability in gastrointestinal disorders and current methods of evaluation
T Vanuytsel, J Tack, R Farre - Frontiers in Nutrition, 2021 - frontiersin.org
An increased intestinal permeability has been described in various gastrointestinal and non-
gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability …
gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability …
Inflammatory pathways in alcoholic steatohepatitis
Inflammatory processes are primary contributors to the development and progression of
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
The gut-liver axis in health and disease: The role of gut microbiota-derived signals in liver injury and regeneration
Z Zheng, B Wang - Frontiers in immunology, 2021 - frontiersin.org
Diverse liver diseases undergo a similar pathophysiological process in which liver
regeneration follows a liver injury. Given the important role of the gut-liver axis in health and …
regeneration follows a liver injury. Given the important role of the gut-liver axis in health and …
Gut–liver axis in alcoholic liver disease
G Szabo - Gastroenterology, 2015 - Elsevier
Alcoholic liver disease (ALD) has been among the leading causes of cirrhosis and liver-
related death worldwide for decades. Early discoveries in alcoholic liver disease identified …
related death worldwide for decades. Early discoveries in alcoholic liver disease identified …
[HTML][HTML] Pathogenesis of alcoholic liver disease: role of oxidative metabolism
E Ceni, T Mello, A Galli - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Alcohol consumption is a predominant etiological factor in the pathogenesis of chronic liver
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …
Alcoholic liver disease: pathogenesis and new therapeutic targets
B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …
[HTML][HTML] Kupffer cells in the liver
LJ Dixon, M Barnes, H Tang, MT Pritchard… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Kupffer cells are a critical component of the mononuclear phagocytic system and are central
to both the hepatic and systemic response to pathogens. Kupffer cells are reemerging as …
to both the hepatic and systemic response to pathogens. Kupffer cells are reemerging as …
Role of gut microbiota in chronic low‐grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies
ICL van den Munckhof, A Kurilshikov… - Obesity …, 2018 - Wiley Online Library
A hallmark of obesity is chronic low‐grade inflammation, which plays a major role in the
process of atherosclerotic cardiovascular disease (ACVD). Gut microbiota is one of the …
process of atherosclerotic cardiovascular disease (ACVD). Gut microbiota is one of the …