The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

Fibroblast growth factor (FGF) signaling pathways are essential regulators of vertebrate
skeletal development. FGF signaling regulates development of the limb bud and formation of …

Fibroblast growth factors (FGFs) are involved in a variety of cellular processes, such as
stemness, proliferation, anti‐apoptosis, drug resistance, and angiogenesis. Here, FGF …

Fibroblast growth factor (FGF) signaling through its receptors, FGFR1, FGFR2, FGFR3, or
FGFR4, regulates cell fate, angiogenesis, immunity, and metabolism. Dysregulated FGF …

Craniosynostosis, the premature fusion of one or more cranial sutures of the skull, provides
a paradigm for investigating the interplay of genetic and environmental factors leading to …

RUNX2 is a master transcription factor of osteoblast differentiation. RUNX2 expression in the
bone and osteogenic front of a suture is crucial for cranial suture closure and membranous …

This article provides an overview of the diagnosis and management of infants with
craniosynostosis. This review also incorporates some of the treatment philosophies followed …

Sagittal craniosynostosis is the most common form of craniosynostosis, affecting
approximately one in 5,000 newborns. We conducted, to our knowledge, the first genome …

Differentiating cells interact with their extracellular environment over time. Chondrocytes
embed themselves in a proteoglycan (PG)-rich matrix, then undergo a developmental …

Craniosynostosis is a pathologic condition associated with the premature fusion of one or
more cranial sutures. When the cranial sutures fuse prematurely, the skull and the growing …