Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Diagnosis of individuals infected by Trypanosoma cruzi is performed mainly by serological
tests using crude antigens, which might crossreact with other infections. In the past ten …

Background Most current guidelines recommend two serological tests to diagnose chronic
Chagas disease. When serological tests are persistently inconclusive, some guidelines …

Background Outbreaks of orally transmitted Trypanosoma cruzi continue to be reported in
Brazil and are associated with a high mortality rate, mainly due to myocarditis. Methods This …

Chagas' disease caused by Trypanosoma cruzi is endemic in Latin America. T. cruzi
presents heterogeneous populations and comprises two main genetic lineages, named T …

BACKGROUND: Blood transfusion is one of the most important transmission routes of
Chagas' disease, a major parasitic infection in Latin America. Therefore, screening for …

A rapid serologic test for diagnosis of T. cruzi infection (Chagas Stat Pak) was developed
using recombinant proteins in an immunochromatographic assay. This cassette format test …

Chagas disease has spread to areas that are nonendemic for the disease with human
migration. Since no single reference standard test is available, serological diagnosis of …

The present systematic review and meta-analysis about the accuracy of diagnostic tests aim
to describe the findings of literature over the last thirty years for the diagnosis of Chagas …

The aim of this work was to determine the best strategy to display antigens (Ags) on
immunochemical devices to improve test selectivity and sensitivity. We comparatively …