Protein corona, understanding the nanoparticle–protein interactions and future perspectives: A critical review

T Kopac - International Journal of Biological Macromolecules, 2021 - Elsevier
Proteins are biopolymers of highly varied structures taking part in almost all processes
occurring in living cells. When nanoparticles (NPs) interact with proteins in biological …

Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery

W Kim, NK Ly, Y He, Y Li, Z Yuan, Y Yeo - Advanced drug delivery reviews, 2023 - Elsevier
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …

Nanoparticles and innate immunity: new perspectives on host defence

D Boraschi, P Italiani, R Palomba, P Decuzzi… - Seminars in …, 2017 - Elsevier
The innate immune system provides the first line of defence against foreign microbes and
particulate materials. Engineered nanoparticles can interact with the immune system in …

Hard and soft protein corona of nanomaterials: Analysis and relevance

R García-Álvarez, M Vallet-Regí - Nanomaterials, 2021 - mdpi.com
Upon contact with a biological milieu, nanomaterials tend to interact with biomolecules
present in the media, especially proteins, leading to the formation of the so-called “protein …

Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

H Mohammad-Beigi, Y Hayashi, CM Zeuthen… - Nature …, 2020 - nature.com
The current understanding of the biological identity that nanoparticles may acquire in a
given biological milieu is mostly inferred from the hard component of the protein corona …

Regulation of macrophage recognition through the interplay of nanoparticle surface functionality and protein corona

K Saha, M Rahimi, M Yazdani, ST Kim, DF Moyano… - ACS …, 2016 - ACS Publications
Using a family of cationic gold nanoparticles (NPs) with similar size and charge, we
demonstrate that proper surface engineering can control the nature and identity of protein …

Fabrication of corona-free nanoparticles with tunable hydrophobicity

DF Moyano, K Saha, G Prakash, B Yan, H Kong… - ACS …, 2014 - ACS Publications
A protein corona is formed at the surface of nanoparticles in the presence of biological fluids,
masking the surface properties of the particle and complicating the relationship between …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Combined effects of nanoplastics and copper on the freshwater alga Raphidocelis subcapitata

A Bellingeri, E Bergami, G Grassi, C Faleri… - Aquatic toxicology, 2019 - Elsevier
Nanoplastics are recognized as able to interact with other pollutants including heavy metals,
and with natural organic matter, with implications for the potential risks to biota. We …

How Entanglement of Different Physicochemical Properties Complicates the Prediction of in Vitro and in Vivo Interactions of Gold Nanoparticles

M Xu, MG Soliman, X Sun, B Pelaz, N Feliu, WJ Parak… - ACS …, 2018 - ACS Publications
The physicochemical properties of a set of 21 different gold nanoparticles (spherical and rod-
shaped nanoparticles (NPs) of different diameters with three different surface coatings) were …