Application of porphyrins in antibacterial photodynamic therapy

BM Amos-Tautua, SP Songca, OS Oluwafemi - Molecules, 2019 - mdpi.com
Antibiotics are commonly used to control, treat, or prevent bacterial infections, however
bacterial resistance to all known classes of traditional antibiotics has greatly increased in the …

[HTML][HTML] Cancer, photodynamic therapy and porphyrin-type derivatives

ATPC Gomes, MG Neves… - Anais da Academia …, 2018 - SciELO Brasil
This review has two parts. The first one gives an approach to interdisciplinary studies
against cancer carried out by many scientists using porphyrin-type substrates as …

[HTML][HTML] Dendritic cells and immunogenic cancer cell death: a combination for improving antitumor immunity

MJ Lamberti, A Nigro, FM Mentucci, NB Rumie Vittar… - Pharmaceutics, 2020 - mdpi.com
The safety and feasibility of dendritic cell (DC)-based immunotherapies in cancer
management have been well documented after more than twenty-five years of …

Porphyrin and phthalocyanine photosensitizers designed for targeted photodynamic therapy of colorectal cancer

K Janas, E Boniewska-Bernacka, G Dyrda… - Bioorganic & medicinal …, 2021 - Elsevier
Colorectal cancer is of particular concern due to its high mortality rate count. Recent
investigations on targeted phototherapy involving novel photosensitizers and drug-delivery …

[HTML][HTML] Light-activated green drugs: How we can use them in photodynamic therapy and mass-produce them with biotechnological tools

E Foresto, P Gilardi, LE Ibarra, IS Cogno - Phytomedicine Plus, 2021 - Elsevier
Photodynamic therapy (PDT) is a promising therapeutic approach to manage the resolution
of cancer. Plants in nature are one of the potential sources for obtaining new …

Effect of peripheral platinum (II) bipyridyl complexes on the interaction of tetra-cationic porphyrins with human serum albumin

OA Chaves, TV Acunha, BA Iglesias, CSH Jesus… - Journal of Molecular …, 2020 - Elsevier
The interaction between human serum albumin (HSA) and two porphyrin-based tetra-
cationic photosensitizers were investigated via spectroscopic techniques (steady-state, time …

[HTML][HTML] Peripheral tetra-cationic Pt (II) porphyrins photo-inactivating rapidly growing mycobacteria: First application in mycobacteriology

GG Rossi, KB Guterres, CH da Silveira, KS Moreira… - Microbial …, 2020 - Elsevier
In this manuscript, we report, for the first time, the photoinactivation evaluation of tetra-
cationic porphyrins with peripheral Pt (II)-bpy complexes in the photodynamic inactivation …

Porphyrin/chlorin derivatives as promising molecules for therapy of colorectal cancer

F Dandash, DY Leger, M Diab-Assaf, V Sol, B Liagre - Molecules, 2021 - mdpi.com
Colorectal cancer (CRC) is a leading cause of cancer-related death. The demand for new
therapeutic approaches has increased attention paid toward therapies with high targeting …

Porphyrin Atropisomerism as a Molecular Engineering Tool in Medicinal Chemistry, Molecular Recognition, Supramolecular Assembly, and Catalysis

S Maguire, G Strachan, K Norvaiša… - … A European Journal, 2024 - Wiley Online Library
Porphyrin atropisomerism, which arises from restricted σ‐bond rotation between the
macrocycle and a sufficiently bulky substituent, was identified in 1969 by Gottwald and …

Supramolecular complex of tetracationic porphyrin with acyclic cucurbituril-like container induces quantitative singlet oxygen generation. Phototoxicity studies in vitro …

S Day, B Pérez, DG Díaz, N Mariño-Ocampo… - … of Photochemistry and …, 2024 - Elsevier
Singlet oxygen generation by porphyrin-based photosensitizers is one of the main strategies
used in the photodynamic therapy of cancerous lesions. In this work, we report that the …