Association of polymorphisms in inflammatory cytokines encoding genes with severe cases of influenza A/H1N1 and B in an Iranian population

M Keshavarz, H Namdari, M Farahmand, P Mehrbod… - Virology journal, 2019 - Springer
Background The increased levels of blood cytokines is the main immunopathological
process that were attributed to severe clinical outcomes in cases of influenza A, influenza B …

Impact of IL-10 gene promoter polymorphisms on treatment response in HCV patients: A systematic review, a meta-analysis, and a meta-regression

T Dhaouadi, A Riahi, T Ben Abdallah… - International Journal …, 2024 - journals.sagepub.com
The impact of interleukin-10 (IL-10) gene promoter polymorphisms (SNPs) on treatment
response in HCV patients was dissimilarly estimated. Hence, the aim of this meta-analysis …

Association of HCV mutated proteins and host SNPs in the development of hepatocellular carcinoma

M Suhail, SS Sohrab, A Qureshi, M Tarique… - Infection, Genetics and …, 2018 - Elsevier
Hepatitis C virus plays a significant role in the development of hepatocellular carcinoma
(HCC) globally. The pathogenic mechanisms of hepatocellular carcinoma with HCV …

Association between IL28B rs12979860 single nucleotide polymorphism and the frequency of colonic Treg in chronically HCV-infected patients

M Mehta, HF Hetta, EA Abdel-Hameed, SD Rouster… - Archives of …, 2016 - Springer
The IL28B gene is associated with spontaneous or treatment-induced HCV viral clearance.
However, the mechanism by which the IL28B single nucleotide polymorphism (SNP) affects …

Association between IFN-λ 3 gene polymorphisms and outcome of treatment with direct acting antivirals in chronic HCV-infected Egyptian patients

I El-Garawani, S Hassab El-Nabi… - Immunological …, 2021 - Taylor & Francis
ABSTRACT Background: Single nucleotide polymorphisms (SNPs) of the interferon lambda
3 (IFN-λ 3) gene are associated with viral clearance and treatment response in chronic …

Single-nucleotide polymorphism of Toll-like receptor 4 and interleukin-10 in response to interferon-based therapy in Egyptian chronic hepatitis C patients

NAH Sadik, OG Shaker, HZ Ghanem, HA Hassan… - Archives of …, 2015 - Springer
Egypt has the highest prevalence of hepatitis C virus (HCV) in the world. It has been
suggested that not only the virus but also the interaction between the virus and the host …

Inflammasome genes' polymorphisms in Egyptian chronic hepatitis C patients: influence on vulnerability to infection and response to treatment

SZK Estfanous, SA Ali, SM Seif… - Mediators of …, 2019 - Wiley Online Library
Chronic inflammation is a pivotal contributor to the liver damage mediated by hepatitis C
virus (HCV). The NOD‐like receptor, pyrin domain‐containing 3 (NLRP3) inflammasome is …

[HTML][HTML] Polymorphisms of IL-10 gene in patients infected with HCV under antiviral treatment in southern Brazil

NMO da Silva, FN Germano, BM Vidales-Braz… - Cytokine, 2015 - Elsevier
Abstract Interleukin-10 (IL-10) is a cytokine that plays an important role in the regulation of
the immune system. Gene polymorphisms of IL-10 have been associated with the different …

[HTML][HTML] Prediction of response to sofosbuvir-based therapy using serum interleukin-12 and single nucleotide polymorphism of the interleukin 28B gene as predictive …

DM Abdelnajid, AY Elmowafy, L Rostaing… - Medicine, 2023 - journals.lww.com
Some hepatitis-C virus patients have resistance to direct-acting-antivirals (DAAs). Genetic
polymorphisms have been associated with drug resistance. This study aimed to evaluate the …

Polymorphism in interferon λ3/interleukin‐28B gene and risk to noncirrhotic chronic hepatitis C genotype 3 virus infection and its effect on the response to combined …

AJ Khan, VA Saraswat, P Ranjan… - Journal of medical …, 2019 - Wiley Online Library
Hepatitis C virus (HCV) infection is a considerable public‐health problem and an important
cause of liver disease with about 71 million people infected worldwide and more than 399 …