Selection of the translational initiation site in most eukaryotic mRNAs appears to occur via a
scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in …

Glycoproteins with O-glycosidically linked carbohydrate chains of complex structures and
functions are found in secretions and on the cell surfaces of cancer cells. The structures of O …

Glycosylation is one of the most common posttranslational modifications of proteins. It has
important roles for protein structure, stability and functions. In vivo the glycostructures …

Sialyltransferases are a family of 10-12 enzymes that catalyze the transfer of sialic acid to
carbohydrate groups of glycoproteins and glycolipids. Three sialyltransferase cDNAs have …

Glycoproteins are proteins that carry N-and O-glycosidically-linked carbohydrate chains of
complex structures and functions. N-glycan chains are assembled in the endoplasmic …

From a systematic search of the UniGene and dbEST databanks, using human β4-
galactosyltransferase (β4GalT-I), which is recognized to function in lactose biosynthesis, as …

Transformation of baby hamster kidney fibroblasts by the Rous sarcoma virus causes a
significant increase in the GlcNAcβ (1, 6) Man-branched oligosaccharides by elevating the …

The baculovirus-insect cell expression system is well-suited for recombinant glycoprotein
production because baculovirus vectors can provide high levels of expression and insect …

Major ampullate silk, also known as dragline silk, is one of the strongest biomaterials known.
This silk is composed of two proteins, major ampullate spidroin 1 (MaSp1) and major …

Most β-1, 4-galactosyltransferase (β-1, 4-GalT)-knockout mice die after birth. Although
several defects were found transiently in these animals, the primary cause of death is …