[HTML][HTML] MicroRNAs in neuroinflammation: implications in disease pathogenesis, biomarker discovery and therapeutic applications

JA Slota, SA Booth - Non-coding RNA, 2019 - mdpi.com
The central nervous system can respond to threat via the induction of an inflammatory
response. Under normal circumstances this response is tightly controlled, however …

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

AS Doghish, O Elazazy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

[HTML][HTML] Exosomal microRNA signatures in multiple sclerosis reflect disease status

S Ebrahimkhani, F Vafaee, PE Young, SSJ Hur… - Scientific reports, 2017 - nature.com
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). There is currently no single definitive test for MS. Circulating …

Biomarkers in multiple sclerosis

A Paul, M Comabella, R Gandhi - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease with a complex
clinical course characterized by inflammation, demyelination, and axonal degeneration …

Exosome‐associated miRNA profile as a prognostic tool for therapy response monitoring in multiple sclerosis patients

I Manna, E Iaccino, V Dattilo, S Barone… - The FASEB …, 2018 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune pathology leading to neurodegeneration. Because
of the complexity and heterogenic etiology of this disease, diagnosis and treatment for …

Expression profile of long non-coding RNAs in serum of patients with multiple sclerosis

M Santoro, V Nociti, M Lucchini, C De Fino… - Journal of Molecular …, 2016 - Springer
Multiple sclerosis (MS) is a chronic progressive inflammatory disease of the central nervous
system (CNS) that leads to severe neurological disability. There is an interest in potential …

B cells from patients with multiple sclerosis induce cell death via apoptosis in neurons in vitro

RP Lisak, L Nedelkoska, JA Benjamins… - Journal of …, 2017 - Elsevier
B cells mediate multiple sclerosis (MS) pathogenesis by mechanisms unrelated to
immunoglobulin (Ig). We reported that supernatants (Sup) from cultured B cells from blood of …

The roles of MicroRNA-141 in human cancers: from diagnosis to treatment

Y Gao, B Feng, S Han, K Zhang, J Chen, C Li… - Cellular Physiology and …, 2016 - karger.com
Cancer remains one of the most threatening causes of human health impairment, and the
mechanisms underlying tumorigenesis have not been completely characterized. MicroRNAs …

Nanocurcumin restores aberrant miRNA expression profile in multiple sclerosis, randomized, double‐blind, placebo‐controlled trial

S Dolati, L Aghebati‐Maleki, M Ahmadi… - Journal of cellular …, 2018 - Wiley Online Library
In the current study, we aimed to identify nanocurcumin effects on microRNAs (miRNAs) in
the peripheral blood of patients with relapsing‐remitting multiple sclerosis (RRMS). We …

Identification of MS-specific serum miRNAs in an international multicenter study

K Regev, BC Healy, A Paul, C Diaz-Cruz… - Neurology …, 2018 - AAN Enterprises
Objective To identify circulating microRNAs (miRNAs) linked to disease, disease stage, and
disability in MS across cohorts. Methods Samples were obtained from the Comprehensive …