[HTML][HTML] Transcatheter embolization therapy in liver cancer: an update of clinical evidences

YXJ Wáng, T De Baere, JM Idée… - Chinese Journal of …, 2015 - ncbi.nlm.nih.gov
Transarterial chemoembolization (TACE) is a form of intra-arterial catheter-based
chemotherapy that selectively delivers high doses of cytotoxic drug to the tumor bed …

Hyperpolarized 13C MRI: A novel approach for probing cerebral metabolism in health and neurological disease

JT Grist, JJ Miller, F Zaccagna… - Journal of Cerebral …, 2020 - journals.sagepub.com
Cerebral metabolism is tightly regulated and fundamental for healthy neurological function.
There is increasing evidence that alterations in this metabolism may be a precursor and …

Investigation of analysis methods for hyperpolarized 13C‐pyruvate metabolic MRI in prostate cancer patients

PEZ Larson, HY Chen, JW Gordon, N Korn… - NMR in …, 2018 - Wiley Online Library
MRI using hyperpolarized (HP) carbon‐13 pyruvate is being investigated in clinical trials to
provide non‐invasive measurements of metabolism for cancer and cardiac imaging. In this …

Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors

JA Bankson, CM Walker, MS Ramirez, W Stefan… - Cancer research, 2015 - AACR
Abstract Hyperpolarized [1-13C]-pyruvate has shown tremendous promise as an agent for
imaging tumor metabolism with unprecedented sensitivity and specificity. Imaging …

Assessing prostate cancer aggressiveness with hyperpolarized dual-agent 3D dynamic imaging of metabolism and perfusion

HY Chen, PEZ Larson, RA Bok, C Von Morze, R Sriram… - Cancer research, 2017 - AACR
New magnetic resonance (MR) molecular imaging techniques offer the potential for
noninvasive, simultaneous quantification of metabolic and perfusion parameters in tumors …

Simultaneous assessment of cardiac metabolism and perfusion using copolarized [1‐13C]pyruvate and 13C‐urea

AZ Lau, JJ Miller, MD Robson… - Magnetic resonance in …, 2017 - Wiley Online Library
Purpose To demonstrate the feasibility of imaging a bolus of co‐polarized [1‐13C] pyruvate
and 13C‐urea to simultaneously assess both metabolism and perfusion in the rodent heart …

Technique development of 3D dynamic CS‐EPSI for hyperpolarized 13C pyruvate MR molecular imaging of human prostate cancer

HY Chen, PEZ Larson, JW Gordon… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose The purpose of this study was to develop a new 3D dynamic carbon‐13
compressed sensing echoplanar spectroscopic imaging (EPSI) MR sequence and test it in …

Studies of metabolism using 13C MRS of hyperpolarized probes

MM Chaumeil, C Najac, SM Ronen - Methods in enzymology, 2015 - Elsevier
First described in 2003, the dissolution dynamic nuclear polarization (DNP) technique,
combined with 13 C magnetic resonance spectroscopy (MRS), has since been used in …

Optimizing flip angles for metabolic rate estimation in hyperpolarized carbon-13 MRI

J Maidens, JW Gordon, M Arcak… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Hyperpolarized carbon-13 magnetic resonance imaging has enabled the real-time
observation of perfusion and metabolism in vivo. These experiments typically aim to …

High spatiotemporal resolution bSSFP imaging of hyperpolarized [1‐13C]pyruvate and [1‐13C]lactate with spectral suppression of alanine and pyruvate‐hydrate

E Milshteyn, C von Morze, JW Gordon… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose The balanced steady‐state free precession (bSSFP) acquisition enables high
spatiotemporal resolution for hyperpolarized 13C MRI at 3T but is limited by spectral …