Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Animal models of human disease: zebrafish swim into view

GJ Lieschke, PD Currie - Nature Reviews Genetics, 2007 - nature.com
Despite the pre-eminence of the mouse in modelling human disease, several aspects of
murine biology limit its routine use in large-scale genetic and therapeutic screening. Many …

Zebrafish as a model vertebrate for investigating chemical toxicity

AJ Hill, H Teraoka, W Heideman… - Toxicological …, 2005 - academic.oup.com
Zebrafish (Danio rerio) has been a prominent model vertebrate in a variety of biological
disciplines. Substantial information gathered from developmental and genetic research …

In vivo drug discovery in the zebrafish

LI Zon, RT Peterson - Nature reviews Drug discovery, 2005 - nature.com
The zebrafish has become a widely used model organism because of its fecundity, its
morphological and physiological similarity to mammals, the existence of many genomic tools …

Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis

EA Greene, CA Codomo, NE Taylor, JG Henikoff… - Genetics, 2003 - academic.oup.com
Chemical mutagenesis has been the workhorse of traditional genetics, but it has not been
possible to determine underlying rates or distributions of mutations from phenotypic screens …

The use of zebrafish to understand immunity

NS Trede, DM Langenau, D Traver, AT Look, LI Zon - Immunity, 2004 - cell.com
For decades immunologists have relied heavily on the mouse model for their experimental
designs. With the realization of the important role innate immunity plays in orchestrating …

Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos

JM Davis, H Clay, JL Lewis, N Ghori, P Herbomel… - Immunity, 2002 - cell.com
Infection of vertebrate hosts with pathogenic Mycobacteria, the agents of tuberculosis,
produces granulomas, highly organized structures containing differentiated macrophages …

tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors

S Berghmans, RD Murphey… - Proceedings of the …, 2005 - National Acad Sciences
TP53 is the most frequently mutated tumor suppressor gene in human cancer, with nearly
50% of all tumors exhibiting a loss-of-function mutation. To further elucidate the genetic …

Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases

B Novoa, A Figueras - Current topics in innate immunity II, 2012 - Springer
The zebrafish (Danio rerio) has been extensively used in biomedical research as a model to
study vertebrate development and hematopoiesis and recently, it has been adopted into …

[图书][B] The toxicology of fishes

RT Di Giulio, DE Hinton - 2008 - taylorfrancis.com
When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …