68Ga-Based Radiopharmaceuticals: Production and Application Relationship

I Velikyan - Molecules, 2015 - mdpi.com
The contribution of 68Ga to the promotion and expansion of clinical research and routine
positron emission tomography (PET) for earlier better diagnostics and individualized …

Bifunctional gallium-68 chelators: Past, present, and future

P Spang, C Herrmann, F Roesch - Seminars in nuclear medicine, 2016 - Elsevier
This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

PRWJ Davey, BM Paterson - Molecules, 2022 - mdpi.com
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

A Step-by-Step Guide for the Novel Radiometal Production for Medical Applications: Case Studies with 68Ga, 44Sc, 177Lu and 161Tb

Z Talip, C Favaretto, S Geistlich, NP Meulen - Molecules, 2020 - mdpi.com
The production of novel radionuclides is the first step towards the development of new
effective radiopharmaceuticals, and the quality thereof directly affects the preclinical and …

Production of radiometals in liquid targets

SJC Do Carmo, PJH Scott, F Alves - EJNMMI Radiopharmacy and …, 2020 - Springer
Over the last several years, the use of radiometals has gained increasing relevance in
supporting the continuous development of new, complementary and more specific biological …

Radiolabeling of DOTA-like conjugated peptides with generator-produced 68Ga and using NaCl-based cationic elution method

D Mueller, WAP Breeman, I Klette, M Gottschaldt… - Nature protocols, 2016 - nature.com
Abstract Gallium-68 (68 Ga) is a generator-produced radionuclide with a short half-life (t ½=
68 min) that is particularly well suited for molecular imaging by positron emission …

Continued rapid growth in 68Ga applications: update 2013 to June 2014

I Velikyan - Journal of Labelled Compounds and …, 2015 - Wiley Online Library
The worldwide utilization of 68Ga‐radionuclide for the fundamental research and clinical
applications is growing exponentially. A broad range of 68Ga‐based imaging agents has …

68Ga-NOTA-UBI-29-41 as a PET tracer for detection of bacterial infection

M Vilche, AL Reyes, E Vasilskis, P Oliver… - Journal of Nuclear …, 2016 - Soc Nuclear Med
The cationic peptide 68Ga-NOTA-UBI-29-41 was synthesized and characterized.
Biodistribution and PET/CT examinations were performed for evaluation of its biologic …

[HTML][HTML] Automated radiosynthesis of 68Ga for large-scale routine production using 68Zn pressed target

AH Alnahwi, S Tremblay, S Ait-Mohand… - Applied Radiation and …, 2020 - Elsevier
Abstract Gallium-68 (68 Ga) has attracted increasing interest in recent years due to the
expanding clinical applications of 68 Ga-based radiopharmaceuticals (Rahbar et al., 2017) …

[HTML][HTML] 68Ga-DOTA and analogs: Current status and future perspectives

K Kilian - Reports of Practical Oncology & Radiotherapy, 2014 - Elsevier
The construction of the 68 Ge/68 Ga generator has increased application of
radiopharmaceuticals labeled with this isotope in medicine. 68 Ga-PET is widely employed …