Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
Metal complexes for therapeutic applications
Metal complexes have been widely used for applications in the chemical and physical
sciences due to their unique electronic and stereochemical properties. For decades the use …
sciences due to their unique electronic and stereochemical properties. For decades the use …
Organometallic anticancer compounds
The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …
Challenges and opportunities in the development of organometallic anticancer drugs
This review provides an introduction into the fascinating area of organometallic anticancer
compounds. Although the subject dates back many years, it has witnessed considerable …
compounds. Although the subject dates back many years, it has witnessed considerable …
Potential of organometallic complexes in medicinal chemistry
SM Qader, AM Muhammed, RA Omer… - Reviews in Inorganic …, 2024 - degruyter.com
Organometallic complexes, which include ligands such as carbon monoxide (CO),
carbenes, alkyls, phenyls, p-bound alkynes, alkenes, cyclopentadienyls, and arenes, have …
carbenes, alkyls, phenyls, p-bound alkynes, alkenes, cyclopentadienyls, and arenes, have …
Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs
SH van Rijt, PJ Sadler - Drug discovery today, 2009 - Elsevier
This review illustrates notable recent progress in the field of medicinal bioinorganic
chemistry as many new approaches to the design of innovative metal-based anticancer …
chemistry as many new approaches to the design of innovative metal-based anticancer …
Nanocarriers for the treatment of glioblastoma multiforme: current state-of-the-art
Glioblastoma multiforme, a grade IV glioma, is the most frequently occurring and invasive
primary tumor of the central nervous system, which causes about 4% of cancer-associated …
primary tumor of the central nervous system, which causes about 4% of cancer-associated …
Underestimated potential of organometallic rhenium complexes as anticancer agents
A Leonidova, G Gasser - ACS chemical biology, 2014 - ACS Publications
In the recent years, organometallic compounds have become recognized as promising anti-
cancer drug candidates. While radioactive 186/188Re compounds are already used in …
cancer drug candidates. While radioactive 186/188Re compounds are already used in …
A new age for iron: antitumoral ferrocenes
From the core of the earth to the core of the archetypal organometallic compound ferrocene,
iron and its compounds contribute to create many aspects of our reality: the earth's …
iron and its compounds contribute to create many aspects of our reality: the earth's …
On the medicinal chemistry of ferrocene
MFR Fouda, MM Abd‐Elzaher… - Applied …, 2007 - Wiley Online Library
Organometallic chemistry and biochemistry have been merged in the last two decades into a
new field: bioorganometallic chemistry. This new research area was devoted to the …
new field: bioorganometallic chemistry. This new research area was devoted to the …