Malaria is the most important parasitic disease worldwide, responsible for an estimated 225
million clinical cases each year. It mainly affects children, pregnant women and non-immune …

Objectives To provide counterevidence to existing literature on healer shopping in Africa
through a systematic analysis of illness practices by Ghanaians with diabetes; to outline …

Background Preventing the emergence of anti-malarial drug resistance is critical for the
success of current malaria elimination efforts. Prevention strategies have focused …

Mutations in Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate
synthase (dhps) genes have been used as means to predict treatment failure to sulfadoxine …

Background Zambia was the first African country to change national antimalarial treatment
policy to artemisinin-based combination therapy–artemether-lumefantrine. An evaluation …

Objective To evaluate treatment practices for uncomplicated malaria after the policy change
from chloroquine to sulfadoxine-pyrimethamine and to artemether-lumefantrine in Zambia …

Abstract Background Drug resistance in Plasmodium falciparum is common in many
endemic and other settings but there is no clear recommendation on when to change …

Although chloroquine (CQ) monotherapy is now generally inadequate for the treatment of
Plasmodium falciparum malaria in northern Ghana—recently, 58% of 225 children failed …

Background Anti-malarial resistance is, and continues to be a significant challenge in the
fight against malaria and a threat to achieving malaria elimination. In Zambia, chloroquine …

Background An artemisinin-based combination therapy, artesunate (AS) plus sulphadoxine-
pyrimethamine (SP), was compared to SP monotherapy to provide evidence of further …