Associations among dietary omega‐3 polyunsaturated fatty acids, the gut microbiota, and intestinal immunity

Y Fu, Y Wang, H Gao, DH Li, RR Jiang… - Mediators of …, 2021 - Wiley Online Library
Omega‐3 polyunsaturated fatty acids (omega‐3 PUFAs), which are essential fatty acids that
humans should obtain from diet, have potential benefits for human health. In addition to …

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease

T Jensen, MF Abdelmalek, S Sullivan, KJ Nadeau… - Journal of …, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically …

Phenyl-γ-valerolactones and phenylvaleric acids, the main colonic metabolites of flavan-3-ols: Synthesis, analysis, bioavailability, and bioactivity

P Mena, L Bresciani, N Brindani, IA Ludwig… - Natural Product …, 2019 - pubs.rsc.org
Covering: 1958 to June 2018 Phenyl-γ-valerolactones (PVLs) and their related
phenylvaleric acids (PVAs) are the main metabolites of flavan-3-ols, the major class of …

Regulatory effects and molecular mechanisms of tea and its active compounds on nonalcoholic fatty liver disease

J Xu, Y Wei, Y Huang, X Wei - Journal of Agricultural and Food …, 2023 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, is a
multifactorial disease resulting from the interaction between environment, genetic …

n-3 polyunsaturated fatty acids in phospholipid or triacylglycerol form attenuate nonalcoholic fatty liver disease via mediating cannabinoid receptor 1/adiponectin …

Y Chen, Z Fan, X Gao, F Zhou, X Guo… - The Journal of …, 2024 - Elsevier
Abstract n-3 polyunsaturated fatty acids (PUFA) have shown to exert beneficial effects in the
treatment of nonalcoholic fatty liver disease (NAFLD). Supplements of n-3 PUFA occur in …

Polyphenols in the prevention and treatment of non-alcoholic fatty liver disease: An update of preclinical and clinical studies

HM Bayram, FM Majoo, A Ozturkcan - Clinical Nutrition ESPEN, 2021 - Elsevier
Background & aims The prevention and treatment of non-alcoholic fatty liver disease
(NAFLD) has become one of the most urgent problems to be solved. To date, only a lifestyle …

APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR mice

MG Pontifex, A Martinsen, RNM Saleh… - The FASEB …, 2021 - Wiley Online Library
The impact of sex and menopausal status in Alzheimer's disease remains understudied
despite increasing evidence of greater female risk, particularly in APOE4 carriers. Utilizing …

[HTML][HTML] Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes

A Costabile, G Corona, K Sarnsamak… - Frontiers in …, 2022 - frontiersin.org
The intestinal microbiota plays an important role in host metabolism via production of dietary
metabolites. Microbiota imbalances are linked to type 2 diabetes (T2D), but dietary …

[HTML][HTML] Differential influence of soluble dietary fibres on intestinal and hepatic carbohydrate response

MG Pontifex, A Mushtaq, G Le Gall, I Rodriguez-Ramiro… - Nutrients, 2021 - mdpi.com
Refined foods are commonly depleted in certain bioactive components that are abundant in
'natural'(plant) foods. Identification and addition of these 'missing'bioactives in the diet is …

[HTML][HTML] Unveiling the role of the fatty acid binding protein 4 in the metabolic-associated fatty liver disease

J Moreno-Vedia, J Girona, D Ibarretxe, L Masana… - Biomedicines, 2022 - mdpi.com
Metabolic-associated fatty liver disease (MAFLD), the main cause of chronic liver disease
worldwide, is a progressive disease ranging from fatty liver to steatohepatitis (metabolic …