[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

The role of next-generation probiotics in obesity and obesity-associated disorders: Current knowledge and future perspectives

NG Vallianou, D Kounatidis, D Tsilingiris… - International Journal of …, 2023 - mdpi.com
Obesity and obesity-associated disorders pose a major public health issue worldwide. Apart
from conventional weight loss drugs, next-generation probiotics (NGPs) seem to be very …

Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

GZ Wei, KA Martin, PY Xing… - Proceedings of the …, 2021 - National Acad Sciences
While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …

The impact of free sugar on human health—a narrative review

KM Gillespie, E Kemps, MJ White, SE Bartlett - Nutrients, 2023 - mdpi.com
The importance of nutrition in human health has been understood for over a century.
However, debate is ongoing regarding the role of added and free sugars in physiological …

Gut microbiota differences according to ultra-processed food consumption in a Spanish population

A Cuevas-Sierra, FI Milagro, P Aranaz, JA Martínez… - Nutrients, 2021 - mdpi.com
Ultra-processed foods (UPFs) consumption could affect gut microbiota diversity and profile.
We aimed to evaluate the effects of UPFs on microbiota, considering the role of sex. The …

Effects of ultra-processed foods on the microbiota-gut-brain axis: The bread-and-butter issue

Z Song, R Song, Y Liu, Z Wu, X Zhang - Food Research International, 2023 - Elsevier
The topic of gut microbiota and the microbiota-gut-brain (MGB) axis has become the
forefront of research and reports in the past few years. The gut microbiota is a dynamic …

The neural basis of sugar preference

WW Liu, DV Bohórquez - Nature Reviews Neuroscience, 2022 - nature.com
When it comes to food, one tempting substance is sugar. Although sweetness is detected by
the tongue, the desire to consume sugar arises from the gut. Even when sweet taste is …

The gut-brain axis mediates bacterial driven modulation of reward signaling

JS Kim, KC Williams, RA Kirkland, R Schade… - Molecular …, 2023 - Elsevier
Objective Our goal is to investigate if microbiota composition modulates reward signaling
and assess the role of the vagus in mediating microbiota to brain communication. Methods …

Probiotics synergized with conventional regimen in managing Parkinson's disease

H Sun, F Zhao, Y Liu, T Ma, H Jin, K Quan… - npj Parkinson's …, 2022 - nature.com
Parkinson's disease (PD) is mainly managed by pharmacological therapy (eg, Benserazide
and dopamine agonists). However, prolonged use of these drugs would gradually diminish …

Diet and gut microbial associations in irritable bowel syndrome according to disease subtype

Y Wang, W Ma, R Mehta, LH Nguyen, M Song… - Gut …, 2023 - Taylor & Francis
The role of diet and the gut microbiome in the etiopathogenesis of irritable bowel syndrome
(IBS) is not fully understood. Therefore, we investigated the interplay between dietary risk …