Assessment of sedative activity of fraxin: In vivo approach along with receptor binding affinity and molecular interaction with GABAergic system

SA Mukty, R Hasan, MS Bhuia, AK Saha… - Drug Development …, 2024 - Wiley Online Library
Insomnia is a sleep disorder in which you have trouble falling and/or staying asleep. This
research aims to evaluate the sedative effects of fraxin (FX) on sleeping mice induced by …

ZiBu PiYin Recipe Regulates Central and Peripheral Aβ Metabolism and Improves Diabetes-associated Cognitive Decline in ZDF Rats

T Bi, R Feng, W Ren, T Hang, T Zhao, L Zhan - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cognitive impairment caused by central neuropathy in
type 2 diabetes mellitus (T2DM), namely diabetes-associated cognitive decline (DACD), is …

Isolation, antioxidant and antifungal activity of furanocoumarins from the leaves of Heracleum vicinum Boiss.

M Liu, S Liu, H Wu, W Zhang, Y Zhang, J Guo, H Yu… - Food Bioscience, 2024 - Elsevier
In this work, coumarin compounds were extracted by ultrasonic-microwave synergistic
extraction from the leaves of Heracleum vicinum Boiss.. The five furanocoumarins …

[HTML][HTML] The Protective Effects of Pistacia Atlantica Gum in a Rat Model of Aluminum Chloride-Induced Alzheimer's Disease via Affecting BDNF and NF-kB

MM Gravandi, SZ Hosseini, SD Alavi… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a neurodegenerative condition characterized by progressive
cognitive deterioration, including deficits in memory and other cognitive functions. Oxidative …

Therapeutic effects of a new bithiophene against aluminum-induced Alzheimer's disease in a rat model: Pathological and ultrastructural approach

K AbdEl-Raouf, MA El-Ganzuri, WM El-Sayed - Tissue and Cell, 2024 - Elsevier
Alzheimer's disease (AD) remains of unknown etiology and lacks a cure. This study aimed to
evaluate the therapeutic potential of a novel bithiophene derivative at two doses against …