Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before
mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to …

Background Whether intravenous thrombolysis (IVT) prior to endovascular thrombectomy
(EVT) provides additional benefits in patients with acute ischemic stroke (AIS) and a large …

Objective To provide a critical appraisal on the evidence from randomized controlled clinical
trials (RCTs) on the utility of direct endovascular treatment (dEVT) compared to the …

Background Endovascular treatment (EVT) has greatly improved the prognosis of acute
ischemic stroke (AIS) patients with a proximal intracranial large vessel occlusion (LVO) of …

Objective In this review and meta-analysis we sought to compare the efficacy and safety of
direct endovascular thrombectomy (EVT) and bridging therapy for intravenous thrombolysis …

Background and Purpose: Recent trials showed thrombectomy alone was comparable to
bridging therapy in patients with anterior circulation large vessel occlusion eligible for both …

Background The use of intravenous thrombolysis (IVT) before mechanical thrombectomy
(MT) for acute ischemic stroke due to large vessel occlusion (AIS-LVO) is a debatable …

Objective To test the hypothesis that IV thrombolysis (IVT) treatment before endovascular
thrombectomy (EVT) is associated with better outcomes in patients with anterior circulation …

To assess the clinical value of mechanical thrombectomy (MT) combined with intravenous
thrombolysis (IVT) in acute ischemic stroke (AIS) by comparing it with the MT alone. In this …